Neuronal type-specific modulation of cognition and AP-1 signaling by early-life rearing conditions. [CUT&Tag]
ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 19 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Mus musculus (mouse)
- Samples
- 19 samples: 6 conditions, mostly in triplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Neuronal type-specific modulation of cognition and AP-1 signaling by early-life rearing conditionsNature communications · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE288333_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1216952 and SRA study SRP560589. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 17 samples.
How we read this: 6 replicated groups read from 19 sample titles; they account for 17 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8765509 CyT, CA1, EE, rep1 CyT, CA1, EE,
- GSM8765510 CyT, CA1, EE, rep2 CyT, CA1, EE,
- GSM8765511 CyT, CA1, SC, rep1 CyT, CA1, SC,
- GSM8765512 CyT, CA1, SC, rep2 CyT, CA1, SC,
- GSM8765513 CyT, CA1, SC, rep3 CyT, CA1, SC,
- GSM8765514 CyT, CA1, IE, rep1 CyT, CA1, IE,
- GSM8765515 CyT, CA1, IE, rep2 CyT, CA1, IE,
- GSM8765516 CyT, CA1, IE, rep3 CyT, CA1, IE,
- GSM8765517 CyT, DG, EE, rep1 CyT, DG, EE,
- GSM8765518 CyT, DG, EE, rep2 CyT, DG, EE,
- GSM8765519 CyT, DG, SC, rep1 CyT, DG, SC,
- GSM8765520 CyT, DG, SC, rep2 CyT, DG, SC,
- GSM8765521 CyT, DG, SC, rep3 CyT, DG, SC,
- GSM8765522 CyT, DG, SC, rep4 CyT, DG, SC,
- GSM8765523 CyT, DG, IE, rep1 CyT, DG, IE,
- GSM8765524 CyT, DG, IE, rep2 CyT, DG, IE,
- GSM8765525 CyT, DG, IE, rep3 CyT, DG, IE,
- GSM8765526 CyT, CA1, SC, IgG
- GSM8765527 CyT, DG, SC, IgG
- GSE202753 DsbA-L deficiency attenuates LPS-induced acute kidney injury via NF-κB/AP-1 regulation of macrophage polarization 13 samples shares ap-1, cut
- GSE306261 Astrocyte glucocorticoid receptor signaling restricts neuronal plasticity [CUT&RUN] 50 samples shares cut, neuronal
- GSE282802 KMT2D controls cerebellar granule cell differentiation by temporally activating neuronal transcriptional factor genes [CUT&RUN] 10 samples shares cut, neuronal
- GSE275917 Nup153 regulates neuronal responsiveness through HDAC1-mediated epigenetic modulation [ChIP-seq] 17 samples shares modulation, neuronal
- GSE200461 The maternal X chromosome impairs cognition and accelerates brain aging through epigenetic modulation in female mice 30 samples shares modulation, cognition
- GSE304211 H4K16ac contributes to chromatin compartment reorganization during mitotic and meiotic transitions [CUTnTAG] 128 samples shares cut
- GSE297309 SKP1A-mediated degradation of PRC2 triggers activation of Polycomb-silenced gene [CUT&Tag] 108 samples shares cut
- GSE289642 Noncanonical PRC2 chromatin association reveals a key role of EZHIP in intergenerational epigenetic memory transition [ChIP-Seq, Cut & Run] 107 samples shares cut
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.