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scRNA seq of Pdgfra+ cells from the mouse intestine

GSE288481 Mus musculus Expression profiling by high throughput sequencing 5 samples Submitted 2025/11/05 Platform GPL34328
Summary
Sorted PDGFRA+cells that were lineage-negative for other major intestinal cell type markers (EPCAM1, TER119, CD45, PECAM1) were obtained from the colon of 5 mice. Briefly, mice were given 2.0% (weight/volume) DSS (Thermo Fisher Scientific, #J14489-22) dissolved in water for 7 days for the acute model of DSS. In the chronic model, DSS-administration was followed by a water recovery phase lasting for another 7 days. This cycle was repeated 2 more times, with mice weights being recorded daily.
Published in
Bidirectional CRISPR screens decode a GLIS3-dependent fibrotic cell circuit
Pokatayev V, Jaiswal A, Shih AR et al. · Nature 2026 · PMID 41501466 · doi:10.1038/s41586-025-09907-x
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Also filed as BioProject PRJNA1217846 and SRA study SRP560946. Searching any of these in the dataset finder brings you back here.

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