Estrogen Receptor 1 Signaling in Hepatic Stellate Cells Designates Resistance to Liver Fibrosis [ChIP-seq]
ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 14 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Mus musculus (mouse)
- Samples
- 14 samples: 14 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE289421_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1222884 and SRA study SRP563490. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 14 sample titles: 14 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8791216 Yjlab_chip_S004_male_input_rep1
- GSM8791217 Yjlab_chip_S005_female_input_rep1
- GSM8791218 Yjlab_chip_S006_male_rep1_k4me1
- GSM8791219 Yjlab_chip_S007_female_rep1_k4me1
- GSM8791220 Yjlab_chip_S008_male_rep2_k4me1
- GSM8791221 Yjlab_chip_S009_female_rep2_k4me1
- GSM8791222 Yjlab_chip_S010_male_rep1_k9me3
- GSM8791223 Yjlab_chip_S011_female_rep1_k9me3
- GSM8791224 Yjlab_chip_S012_male_rep2_k9me3
- GSM8791225 Yjlab_chip_S013_female_rep2_k9me3
- GSM8791226 Yjlab_chip_S014_male_rep1_k27ac
- GSM8791227 Yjlab_chip_S015_female_rep1_k27ac
- GSM8791228 Yjlab_chip_S016_male_rep2_k27ac
- GSM8791229 Yjlab_chip_S017_female_rep2_k27ac
- GSE313359 Hippocampal estrogen levels, receptor types and epigenetics contribute to sex-specific memory-vulnerabilities to concurrent acute stresses [Cut & Run] 45 samples shares estrogen, receptor
- GSE326173 Nuclear receptor Nur77 resolves the inflammatory response of macrophages primarily by regulating expression of AP-1 transcription factors and their target genes [ChIP-seq] 42 samples shares receptor, chip-seq
- GSE324864 HP1B and H3K9me3 Regulate Olfactory Receptor Choice and 2 Transcriptional Identity [ChIP-seq] 28 samples shares receptor, chip-seq
- GSE314584 Toll-Like-Receptor 5 Reduces Lung Dysbiosis and Protects Against Pulmonary Fibrosis 124 samples shares receptor, fibrosis
- GSE268029 Transcriptomic profiling of the oocyte-cumulus-granulosa cell complex from estrogen receptor beta knockout mice 93 samples shares estrogen, receptor
- GSE248864 Hepatic Glucocorticoid Receptor (GR) drives the diurnal adaptation to Caloric Restriction 90 samples shares receptor, hepatic
- GSE317602 Lung gene expression in WT and estrogen receptor alpha and beta knockout mice exposed to house dust mites 72 samples shares estrogen, receptor
- GSE288662 Role of progesterone receptor in inguinal hernia formation via skeletal muscle fibrosis [Hernia_Multiomics] 20 samples shares receptor, fibrosis
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.