Role of ATF4 in regulation of kidney gene expressions, signaling pathways and functions [mouse]
RNA-seq (gene expression) · mouse · 17 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 17 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Deletion of the transcription factor ATF4 in a model of clear cell renal cell carcinomaNeoplasia (New York, N.Y.) · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE291047_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1231460 and SRA study SRP567824. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 17 more — browse all 17 samples with per-sample file links →
- GSE336472 Knockdown and knockout of the Integrated Stress Response (ISR) and ATF4 in cultures of adult mouse dorsal root ganglia 28 samples shares atf4
- GSE303929 Comparative Transcriptomic Analysis of Embryonic Hearts in Atf4 Exon 2 and Exon 2–3 Conditional Knockout Mice 16 samples shares atf4
- GSE291610 Splice isoform-perturbation coupled to single cell transcriptome profiling reveals functions of microexons in neurogenesis and autism-linked pathways [snRNA-Seq] 96 samples shares functions
- GSE302857 Multi-tier signaling and epigenomic reprogramming drive microglial inflammatory states and functions associated with demyelination [RNA-seq] 81 samples shares functions
- GSE330842 GALNT3-deletion suppresses inflammation-associated fibrosis to ameliorates chronic kidney disease via inactivating the TNF-α/NF-kB/MAPK signaling pathway 9 samples shares kidney
- GSE305975 Basal level of ATF4 promotes T cell readiness for activation-induced proliferation 29 samples shares atf4
- GSE281440 Pre-occupied ATF4 relies on CEBPγ co-binding for robust transcription activation during integrated stress response [CUT&Tag] 20 samples shares atf4
- GSE267650 Mouse kidney ischemia-reperfusion injury time course 57 samples shares kidney
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.