Basal level of ATF4 promotes T cell readiness for activation-induced proliferation
ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 29 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Mus musculus (mouse)
- Samples
- 29 samples: 8 conditions, mostly in duplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Basal level of ATF4 promotes T cell readiness for activation-induced proliferationiScience · 2026
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE305975_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1308574 and SRA study SRP560230. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 16 samples.
How we read this: 8 replicated groups read from 29 sample titles; they account for 16 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8759839 Mus CD8+ T cell, WT, 0h
- GSM8759840 Mus CD8+ T cell, KO, 0h
- GSM8759841 Mus CD8+ T cell, WT, 12h , rep1 Mus CD8+ T cell, WT, 12…
- GSM8759842 Mus CD8+ T cell, WT, 12h , rep2 Mus CD8+ T cell, WT, 12…
- GSM8759843 Mus CD8+ T cell, KO, 12h , rep1 Mus CD8+ T cell, KO, 12…
- GSM8759844 Mus CD8+ T cell, KO, 12h , rep2 Mus CD8+ T cell, KO, 12…
- GSM8759845 Mus CD8+ T cell, WT, 24h , rep1 Mus CD8+ T cell, WT, 24…
- GSM8759846 Mus CD8+ T cell, WT, 24h , rep2 Mus CD8+ T cell, WT, 24…
- GSM8759847 Mus CD8+ T cell, KO, 24h , rep1 Mus CD8+ T cell, KO, 24…
- GSM8759848 Mus CD8+ T cell, KO, 24h , rep2 Mus CD8+ T cell, KO, 24…
- GSM8759849 Mus CD8+ T cell, WT, 48h , rep1 Mus CD8+ T cell, WT, 48…
- GSM8759850 Mus CD8+ T cell, WT, 48h , rep2 Mus CD8+ T cell, WT, 48…
- GSM8759851 Mus CD8+ T cell, KO, 48h , rep1 Mus CD8+ T cell, KO, 48…
- GSM8759852 Mus CD8+ T cell, KO, 48h , rep2 Mus CD8+ T cell, KO, 48…
- GSM9187071 Mus CD8+ T cell, C57BL/6J , active 12h, ATF4, biol rep 1, (ChIP)
- GSM9187072 Mus CD8+ T cell, C57BL/6J , active 12h, ATF4, biol rep 2, (ChIP)
- GSM9187073 Mus CD8+ T cell, C57BL/6J , active 12h, ATF4, biol rep 3, (ChIP)
- GSM9187074 Mus CD8+ T cell, C57BL/6J , active 48h, ATF4, biol rep 1, (ChIP)
- GSM9187075 Mus CD8+ T cell, C57BL/6J , active 48h, ATF4, biol rep 2, (ChIP)
- GSM9187076 Mus CD8+ T cell, C57BL/6J , active 48h, ATF4, biol rep 3, (ChIP)
- GSM9187077 Mus CD8+ T cell, C57BL/6J , active 12h, IgG, biol rep 1, (INPUT)
- GSM9187078 Mus CD8+ T cell, C57BL/6J , active 12h, IgG, biol rep 2, (INPUT)
- GSM9187079 Mus CD8+ T cell, C57BL/6J , active 12h, IgG, biol rep 3, (INPUT)
- GSM9187080 Mus CD8+ T cell, C57BL/6J , active 12h, IgG, biol rep 4, (INPUT)
- GSM9187081 Mus CD8+ T cell, C57BL/6J , active 48h, IgG, (INPUT)
- GSM9187082 Mus CD8+ T cell, KO, active 12h,biol rep 1 Mus CD8+ T cell, KO, ac…
- GSM9187083 Mus CD8+ T cell, KO, active 12h,biol rep 2 Mus CD8+ T cell, KO, ac…
- GSM9187084 Mus CD8+ T cell, WT, active 12h,biol rep 1 Mus CD8+ T cell, WT, ac…
- GSM9187085 Mus CD8+ T cell, WT, active 12h,biol rep 2 Mus CD8+ T cell, WT, ac…
- GSE288143 Basal level of ATF4 promotes T cell readiness for activation-induced proliferation [RNA-seq] 14 samples shares atf4, activation-induced, proliferation, readiness, promotes, basal, level
- GSE305890 Basal level of ATF4 promotes T cell readiness for activation-induced proliferation [CUT&Run] 11 samples shares atf4, activation-induced, proliferation, readiness, promotes, basal, level
- GSE235798 Atf4 promotes erythroid differentiation by regulating ribosome biogenesis via RPS19BP1 6 samples shares atf4, promotes
- GSE248653 Nicotinamide mononucleotide promotes female germline stem cell proliferation by activating the H4K16ac-Hmgb1-Fyn-PLD signaling pathway through epigenetic remodeling 20 samples shares proliferation, promotes
- GSE226831 Metformin Promotes Proliferation of Mouse Female Germline Stem Cells by Histone Acetylation Modification of Traf2 12 samples shares proliferation, promotes
- GSE300925 Lyn expression in macrophages promotes TLR activation and restricts proliferation in an isoform-independent manner 48 samples shares proliferation, promotes
- GSE295816 Tissue factor pathway inhibitor promotes the migration, proliferation and colonization of MSCs by regulating CXCL12/CXCR4 signaling pathway 20 samples shares proliferation, promotes
- GSE295541 TCN2 promotes psoriatic skin inflammation and keratinocyte proliferation via the IL-1β-STAT3 pathway 12 samples shares proliferation, promotes
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.