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Mosquito salivary sialokinin reduces human primary monocyte activation

GSE291153 Homo sapiens Expression profiling by high throughput sequencing 6 samples Submitted 2025/08/28 Platform GPL24106
Summary
Mosquito saliva contains bioactive factors that enhance viral infection, with sialokinin identified as a key contributor to vascular leakage and viral spread in mice. Understanding effect of sialokinin on human moncoytes, the most important innate cells that responsible for the viral-induced inflammatory, will provide important insight to host-virus-vector interaction in arbovirus infection.
Published in
Mosquito salivary sialokinin reduces monocyte activation and chikungunya virus-induced inflammation via neurokinin receptors
Fong SW, Tan JJL, Sridhar V et al. · Nature communications 2025 · PMID 41115926 · doi:10.1038/s41467-025-64468-x
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Also filed as BioProject PRJNA1232099 and SRA study SRP568083. Searching any of these in the dataset finder brings you back here.

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