Bulk RNA-seq analysis of molecular characteristics induced by Aoah over-expression in MYC-Luc spontaneous hepatocellular carcinoma tumors
RNA-seq (gene expression) · mouse · 14 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 14 samples: 4 × Luc-A vs 4 × Luc-V vs 3 × LucOS-A vs 3 × LucOS-VGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Cancer immunology data engine reveals secreted AOAH as a potential immunotherapyCell · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE291586_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1234191 and SRA study SRP569311. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 14 samples.
How we read this: 4 replicated groups read from 14 sample titles; they account for 14 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8838077 Luc-A1 Luc-A
- GSM8838078 Luc-A2 Luc-A
- GSM8838079 Luc-A3 Luc-A
- GSM8838080 Luc-A4 Luc-A
- GSM8838081 LucOS-A1 LucOS-A
- GSM8838082 LucOS-A2 LucOS-A
- GSM8838083 LucOS-A3 LucOS-A
- GSM8838084 LucOS-V1 LucOS-V
- GSM8838085 LucOS-V2 LucOS-V
- GSM8838086 LucOS-V3 LucOS-V
- GSM8838087 Luc-V1 Luc-V
- GSM8838088 Luc-V2 Luc-V
- GSM8838089 Luc-V3 Luc-V
- GSM8838090 Luc-V4 Luc-V
- GSE291594 Single-cell analysis of immune cell characteristics induced by Aoah over-expression in MYC-Luc spontaneous hepatocellular carcinoma tumors 24 samples shares characteristics, over-expression, hepatocellular, spontaneous, induced, myc-luc
- GSE291587 Bulk RNA-seq analysis of molecular characteristics induced by Aoah over-expression in B16 subcutaneous implanted tumors 12 samples shares characteristics, over-expression, rna-seq, induced, bulk
- GSE291354 Bulk RNA-seq analysis of gene expression characteristics induced by Adamts7 over-expression in B2905-M4 subcutaneous implanted tumors 10 samples shares characteristics, over-expression, rna-seq, induced, bulk
- GSE291584 Bulk RNA-seq analysis of molecular characteristics induced by Cr1l over-expression in B16mhgp100 subcutaneous implanted tumors 7 samples shares characteristics, over-expression, rna-seq, induced, bulk
- GSE270414 Precision targeting of beta-catenin induces tumor reprogramming and immunity in hepatocellular cancers [Bulk RNA-seq CTNNB1/hMet/NFE2L2] 13 samples shares hepatocellular, rna-seq, bulk
- GSE290449 Precision targeting of beta-catenin induces tumor reprogramming and immunity in hepatocellular cancers [Bulk RNA-seq CTNNB1/NFE2L2] 9 samples shares hepatocellular, rna-seq, bulk
- GSE316139 Studying the role of humanized-TLR8 on immune cell dynamics in the placental microenvironment in a spontaneous mouse model of aPL-induced pregnancy loss 57 samples shares spontaneous, induced
- GSE262315 Comprehensive Analysis of Phenotypes and Transcriptome Characteristics Reveal the Best Atopic Dermatitis Mouse Model Induced by MC903 34 samples shares characteristics, induced
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.