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Effect of SIRT6 on renal tubular cells in diabetic kidney disease

GSE291755 Mus musculus Expression profiling by high throughput sequencing 6 samples Submitted 2026/07/08 Platform GPL24247
Summary
To explore the role of SIRT6 in renal tubular epithelial cells in DKD mice, we extracted primary renal tubular epithelial cells from wild-type and tubular epithelial SIRT6-specific knockout DKD mice, respectively.
Published in
Mitigation of renal tubular injury by SIRT6 may improve individual outcomes in diabetic kidney disease-potential mechanisms involving epigenetic repression of inflammatory responses
Jin Q, Li L, Qu P et al. · Journal of advanced research 2026 · PMID 41076119 · doi:10.1016/j.jare.2025.10.008
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Also filed as BioProject PRJNA1235196 and SRA study SRP569875. Searching any of these in the dataset finder brings you back here.

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