Distinct molecular mechanisms of stress habituation in the mouse hippocampus
ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 266 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Mus musculus (mouse)
- Samples
- 266 samples: 44 conditions, mostly with about 8 replicates eachGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Distinct mechanisms of transcriptomic habituation to repeated stress in the mouse hippocampusNature communications · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE292240_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1237711 and SRA study SRP571261. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 266 samples.
How we read this: 44 replicated groups read from 266 sample titles; they account for 266 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8853405 Handling_1h30min_CRS1_v1 Handling_1h30min_CRS1_v
- GSM8853406 Handling_3h_CRS1_v10 Handling_3h_CRS1_v
- GSM8853407 Handling_0min_CRS1_v11 Handling_0min_CRS1_v
- GSM8853408 Handling_24h_CRS1_v12 Handling_24h_CRS1_v
- GSM8853409 Handling_0min_CRS1_v13 Handling_0min_CRS1_v
- GSM8853410 Handling_1h30min_CRS1_v14 Handling_1h30min_CRS1_v
- GSM8853411 Handling_24h_CRS1_v15 Handling_24h_CRS1_v
- GSM8853412 Handling_24h_CRS1_v16 Handling_24h_CRS1_v
- GSM8853413 Handling_45min_CRS1_v17 Handling_45min_CRS1_v
- GSM8853414 Handling_3h_CRS1_v18 Handling_3h_CRS1_v
- GSM8853415 Handling_5h30min_CRS1_v19 Handling_5h30min_CRS1_v
- GSM8853416 Handling_5h30min_CRS1_v2 Handling_5h30min_CRS1_v
- GSM8853417 Handling_5h30min_CRS1_v20 Handling_5h30min_CRS1_v
- GSM8853418 Handling_3h_CRS1_v21 Handling_3h_CRS1_v
- GSM8853419 Handling_45min_CRS1_v22 Handling_45min_CRS1_v
- GSM8853420 Handling_1h30min_CRS1_v23 Handling_1h30min_CRS1_v
- GSM8853421 Handling_0min_CRS1_v24 Handling_0min_CRS1_v
- GSM8853422 Handling_45min_CRS1_v25 Handling_45min_CRS1_v
- GSM8853423 Handling_3h_CRS1_v26 Handling_3h_CRS1_v
- GSM8853424 Handling_5h30min_CRS1_v27 Handling_5h30min_CRS1_v
- GSM8853425 Handling_0min_CRS1_v28 Handling_0min_CRS1_v
- GSM8853426 Handling_24h_CRS1_v29 Handling_24h_CRS1_v
- GSM8853427 Handling_3h_CRS1_v3 Handling_3h_CRS1_v
- GSM8853428 Handling_5h30min_CRS1_v30 Handling_5h30min_CRS1_v
- GSM8853429 Handling_0min_CRS1_v31 Handling_0min_CRS1_v
- GSM8853430 Handling_24h_CRS1_v32 Handling_24h_CRS1_v
- GSM8853431 Handling_1h30min_CRS1_v33 Handling_1h30min_CRS1_v
- GSM8853432 Handling_45min_CRS1_v34 Handling_45min_CRS1_v
- GSM8853433 Handling_3h_CRS1_v35 Handling_3h_CRS1_v
- GSM8853434 Handling_1h30min_CRS1_v36 Handling_1h30min_CRS1_v
- GSM8853435 Handling_3h_CRS1_v37 Handling_3h_CRS1_v
- GSM8853436 Handling_0min_CRS1_v38 Handling_0min_CRS1_v
- GSM8853437 Handling_24h_CRS1_v39 Handling_24h_CRS1_v
- GSM8853438 Handling_1h30min_CRS1_v4 Handling_1h30min_CRS1_v
- GSM8853439 Handling_45min_CRS1_v40 Handling_45min_CRS1_v
- GSM8853440 Handling_5h30min_CRS1_v41 Handling_5h30min_CRS1_v
- GSM8853441 Handling_1h30min_CRS1_v42 Handling_1h30min_CRS1_v
- GSM8853442 Handling_45min_CRS1_v43 Handling_45min_CRS1_v
- GSM8853443 Handling_24h_CRS1_v44 Handling_24h_CRS1_v
- GSM8853444 Handling_0min_CRS1_v45 Handling_0min_CRS1_v
+ 226 more — browse all 266 samples with per-sample file links →
- GSE292224 Distinct molecular mechanisms of stress habituation in the mouse hippocampus [bulk RNA-seq] 190 samples shares habituation, hippocampus, distinct, stress
- GSE329024 Distinct HPO axis responses to chronic unpredictable stress in young versus adult female mice 63 samples shares distinct, stress
- GSE333807 Single-nucleus multiomic profiling of hippocampus and frontal cortex in a C9orf72 knockout mouse model 52 samples shares hippocampus
- GSE214191 Oxidative Stress Converts Benign Lesions to Cancer via a Self-Amplifying NRF2-EZH2 Loop 63 samples shares stress
- GSE341379 Distinct histone 3 lysine methylation states underlie tumor immune surveillance 50 samples shares distinct
- GSE157232 The CD8+ T cell tolerance checkpoint triggers a transcriptionally and epigenetically distinct differentiation state defined by protein translation defects 30 samples shares distinct
- GSE319614 Bulk RNA-seq transcriptome profiling of hippocampus across 17 autism spectrum disorder mouse models 269 samples shares hippocampus
- GSE272755 Transcriptional effects of lysosome stress on mouse bone marrow-derived macrophages and primary microglia 263 samples shares stress
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.