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Effect of hypoxia on murine splenic NK cells

GSE292263 Mus musculus Expression profiling by high throughput sequencing 6 samples Submitted 2026/02/17 Platform GPL28457
Summary
NK cells responses can be significantly affected by microenvironmental conditions. In pathological conditions, oxygen concentration in tissues can be reduced, lading to hypoxia. Here, we investigated how prolonged exposure to hypoxia affects the transcriptome of murine splenic NK cells.
Published in
Functional segregation of HIF-1α and AhR controls NK cell responsiveness under hypoxia
Giorgetta S, Cortopassi F, Chanis T et al. · iScience 2026 · PMID 42006290 · doi:10.1016/j.isci.2026.115492
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Also filed as BioProject PRJNA1237779 and SRA study SRP571324. Searching any of these in the dataset finder brings you back here.

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