RNA-seq analysis of concentration-response transcriptomic changes induced by cannabichromene (CBC) in hepatocytes derived from human induced pluripotent stem cells (iPSCs)
RNA-seq (gene expression) · human · 24 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 24 samples: 8 conditions, mostly in triplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- An updated comparison of microarray and RNA-seq for concentration response transcriptomic study: case studies with two cannabinoids, cannabichromene and cannabinolBMC genomics · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE292355_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1238242 and SRA study SRP571695. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 24 samples.
How we read this: 8 replicated groups read from 24 sample titles; they account for 24 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8857377 CBC 0.0 μM (control), biol rep1 CBC 0.0 μM (control), b…
- GSM8857378 CBC 0.0 μM (control), biol rep2 CBC 0.0 μM (control), b…
- GSM8857379 CBC 0.0 μM (control), biol rep3 CBC 0.0 μM (control), b…
- GSM8857380 CBC 0.1 μM, biol rep1 CBC 0.1 μM, biol
- GSM8857381 CBC 0.1 μM, biol rep2 CBC 0.1 μM, biol
- GSM8857382 CBC 0.1 μM, biol rep3 CBC 0.1 μM, biol
- GSM8857383 CBC 0.5 μM, biol rep1 CBC 0.5 μM, biol
- GSM8857384 CBC 0.5 μM, biol rep2 CBC 0.5 μM, biol
- GSM8857385 CBC 0.5 μM, biol rep3 CBC 0.5 μM, biol
- GSM8857386 CBC 1.0 μM, biol rep1 CBC 1.0 μM, biol
- GSM8857387 CBC 1.0 μM, biol rep2 CBC 1.0 μM, biol
- GSM8857388 CBC 1.0 μM, biol rep3 CBC 1.0 μM, biol
- GSM8857389 CBC 5.0 μM, biol rep1 CBC 5.0 μM, biol
- GSM8857390 CBC 5.0 μM, biol rep2 CBC 5.0 μM, biol
- GSM8857391 CBC 5.0 μM, biol rep3 CBC 5.0 μM, biol
- GSM8857392 CBC 10 μM, biol rep1 CBC 10 μM, biol
- GSM8857393 CBC 10 μM, biol rep2 CBC 10 μM, biol
- GSM8857394 CBC 10 μM, biol rep3 CBC 10 μM, biol
- GSM8857395 CBC 20 μM, biol rep1 CBC 20 μM, biol
- GSM8857396 CBC 20 μM, biol rep2 CBC 20 μM, biol
- GSM8857397 CBC 20 μM, biol rep3 CBC 20 μM, biol
- GSM8857398 CBC 40 μM, biol rep1 CBC 40 μM, biol
- GSM8857399 CBC 40 μM, biol rep2 CBC 40 μM, biol
- GSM8857400 CBC 40 μM, biol rep3 CBC 40 μM, biol
- GSE292356 RNA-seq analysis of concentration-response transcriptomic changes induced by cannabinol (CBN) in hepatocytes derived from human induced pluripotent stem cells (iPSCs) 21 samples shares concentration-response, hepatocytes, pluripotent, rna-seq, changes, induced
- GSE293032 Transcriptomic comparison of hepatocytes derived from a panel of human induced pluripotent stem cells with different ethnicities 54 samples shares hepatocytes, pluripotent, induced
- GSE254235 Gene expression profiling in human primary hepatocytes and human induced pluripotent stem cell-derived hepatocytes before and after IL-1β Treatment 12 samples shares hepatocytes, pluripotent, induced
- GSE243384 Two-dimensionally cultured functional hepatocytes generated from human induced pluripotent stem cell-derived hepatic organoids for pharmaceutical research 9 samples shares hepatocytes, pluripotent, induced
- GSE228249 Transcriptome analysis of primary human hepatocytes-derived organoids [RNA-seq] 82 samples shares hepatocytes, rna-seq
- GSE226019 Restored glyoxylate metabolism in induced-hepatocytes after CRISPR/Cas-mediated AGXT gene correction and direct cell reprogramming of Primary Hyperoxaluria Type 1 fibroblasts 39 samples shares hepatocytes, induced
- GSE210140 Gene expression profiling of stress-induced senescence and paracrine senecence in human hepatocytes 20 samples shares hepatocytes, induced
- GSE182604 Integrative gene regulatory analysis reveals transcriptional mechanisms required in mature human hepatocytes and during in vitro hepatocyte differentiation (scRNA-Seq) 18 samples shares hepatocytes, rna-seq
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.