Gene expression profiling of stress-induced senescence and paracrine senecence in human hepatocytes
RNA-seq (gene expression) · human · 20 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 20 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE210140_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA864038 and SRA study SRP388940. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 20 more — browse all 20 samples with per-sample file links →
- GSE267788 Mechanical stretch induces senescence of alveolar epithelial cells and drives fibroblast activation by paracrine mechanisms 25 samples shares senescence, paracrine
- GSE267787 Mechanical stretch induces senescence of alveolar epithelial cells and drives fibroblast activation by paracrine mechanisms III 10 samples shares senescence, paracrine
- GSE284666 SenCat: Redefining human cell senescence through multiomic profiling of multiple senescent cell types 190 samples shares senescence
- GSE302932 Transcriptomic profiling of chlorogenic acid and taurine treatment in human skin cells provides insights into cellular senescence mechanisms 36 samples shares senescence
- GSE253279 Single-Cell Gene Expression Profiling reveals distinct exhaustion and senescence signatures in T cells across various types of male infertility 15 samples shares senescence
- GSE328981 Quantum Molecular Resonance attenuates an oxidative stress-induced chimeric transcriptome program in human retinal pigment epithelial cells, preserving RNA structural fidelity 108 samples shares stress-induced
- GSE310729 Age-independent and targetable transcription factor networks regulate CD8+ T cell senescence in aging humans 83 samples shares senescence
- GSE228249 Transcriptome analysis of primary human hepatocytes-derived organoids [RNA-seq] 82 samples shares hepatocytes
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.