Super-enhancers-driven SOX4/SMAD3 enhances AXL signaling via membrane phospholipid remodeling to accelerate leukemia progression [ChIP-seq]
ChIP-seq / ATAC-seq (genome binding and open chromatin) · human · 20 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Homo sapiens (human)
- Samples
- 20 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Super-Enhancer-Driven SOX4/SMAD3 Mediate Membrane Remodeling by Regulating Phospholipid Metabolism to Accelerate Leukemia ProgressionAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE292716_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1241145 and SRA study SRP580766. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 20 more — browse all 20 samples with per-sample file links →
- GSE292718 Super-enhancers-driven SOX4/SMAD3 enhances AXL signaling via membrane phospholipid remodeling to accelerate leukemia progression [CUT&Tag] 16 samples shares smad3, sox4, axl, super-enhancers-driven, phospholipid, progression, remodeling, accelerate
- GSE292717 Super-enhancers-driven SOX4/SMAD3 enhances AXL signaling via membrane phospholipid remodeling to accelerate leukemia progression [RNA-Seq] 42 samples shares smad3, sox4, axl, super-enhancers-driven, phospholipid, progression, remodeling, accelerate
- GSE300358 TGFβ signaling promotes cell cycle progression and resistance to the CDK4/6 inhibitor palbociclib through SOX4 transcriptional modulation in breast cancer cells 40 samples shares sox4, progression
- GSE292576 XPO1 R749Q Mutation Drives Endometrial Cancer Progression by Activating HIF-1/2α–AXL–PI3K/MAPK Signaling 6 samples shares axl, progression
- GSE250129 SOX4 promotes T cell acute lymphoblastic leukemia progression 4 samples shares sox4, progression
- GSE330470 ChIP-seq and CUT&Tag profiling of the genome binding of YAP/TAZ-TEAD and SMAD3 in the human HCC cell line HCCLM3 [ChIP-seq] 55 samples shares smad3
- GSE330469 ChIP-seq and CUT&Tag profiling of the genome binding of YAP/TAZ-TEAD and SMAD3 in the human HCC cell line HCCLM3 [CUT&Tag] 24 samples shares smad3
- GSE308412 Super-enhancer–mediated SMAD3–NR2F2–ID3 transcriptional complex orchestrates Osimertinib resistance in non-small cell lung cancer [CUT&Tag] 15 samples shares smad3
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.