NAT10-mediated β-hydroxybutyrylation Facilitates DNA Replication, Reduces Replication Stress and Genomic Instability
ChIP-seq / ATAC-seq (genome binding and open chromatin) · human · 12 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Homo sapiens (human)
- Samples
- 12 samples: 3 × A vs 3 × B vs 3 × C vs 3 × DGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE292952_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1242228 and SRA study SRP573434. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 12 samples.
How we read this: 4 replicated groups read from 12 sample titles; they account for 12 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8870171 A1 A
- GSM8870172 A2 A
- GSM8870173 A3 A
- GSM8870174 B1 B
- GSM8870175 B2 B
- GSM8870176 B3 B
- GSM8870177 C1 C
- GSM8870178 C2 C
- GSM8870179 C3 C
- GSM8870180 D1 D
- GSM8870181 D2 D
- GSM8870182 D3 D
- GSE271990 Replication Stress Causes Mitotic Nuclear Envelope Reassembly Defect 36 samples shares replication, stress
- GSE310050 Complex interplay between FMRP and DHX9 during DNA replication stress 32 samples shares replication, stress
- GSE298728 SLX4IP limits replication stress globally and at ALT telomeres 16 samples shares replication, stress
- GSE281129 Ongoing replication stress tolerance and clonal T cell responses distinguish liver and lung recurrence and outcomes in pancreatic cancer 794 samples shares replication, stress
- GSE268776 Multi-omics approaches reveal that Diffuse Midline Gliomas are susceptible to replication stress therapy and cholesterol biosynthesis inhibition [RNA-seq] 64 samples shares replication, stress
- GSE318822 MED26 facilitates Mediator–Pol II complex assembly and promotes nuclear stress body formation during heat stress 63 samples shares facilitates, stress
- GSE325334 Restraint of Powassan virus replication by TRIM5a facilitates viral avoidance of antiviral immunity 30 samples shares facilitates, replication
- GSE322526 PI3K-AKT activation determines oncogenic RAS-induced hypertranscription and replication stress 30 samples shares replication, stress
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.