← BioTransfer GEO Dataset Finder
GEO series

Microglia and myeloid cell populations of the developing mouse retina

GSE293912 Mus musculus Expression profiling by high throughput sequencing 7 samples Submitted 2025/04/08 Platform GPL32159Platform GPL24247
Summary
Microglia make important contributions to central nervous system (CNS) development, but the breadth of their distinct developmental functions remain poorly understood. The mouse retina has been a key model system for understanding fundamental mechanisms controlling assembly of the CNS. To gain insight into where and how microglia might influence retinal development, here we identified molecularly unique myeloid cell populations that are selectively present during development, and characterized their anatomical locations. Development-specific transcriptional states were identified using single-cell (sc) and single-nucleus (sn) RNA-sequencing (RNA-seq) across multiple timepoints: postnatal day (P)5, P10, and P17. Transcriptional states were validated in vivo by histological staining for key RNA and/or protein markers.
Published in
Microglia and Myeloid Cell Populations of the Developing Mouse Retina
Martineau S, Valdez-Lopez JC, Zarnick S et al. · Glia 2026 · PMID 41388751 · doi:10.1002/glia.70115
This dataset
Download

Direct links to NCBI, no account and no request form: the whole study as GSE293912_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 7 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1247415 and SRA study SRP576838. Searching any of these in the dataset finder brings you back here.

Samples in this study

The sample list for this study is not cached yet. Press Sort into groups and it will be fetched from NCBI.

+ 7 more — browse all 7 samples with per-sample file links →

Similar datasets

Search all mouse RNA-seq datasets in GEO →

Share this dataset

Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.