Effects of Amino Acid Restriction on Decidualization of Human Endometrial Stromal Cells
RNA-seq (gene expression) · human · 12 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 12 samples: 3 × UD vs 3 × D vs 3 × UD HF vs 3 × D HFGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Amino Acid Restriction Impairs Human Endometrial Stromal Cell Decidualization and Is Rescued by Proline SupplementationJournal of cellular and molecular medicine · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE294481_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1250281 and SRA study SRP578360. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 12 samples.
How we read this: 4 replicated groups read from 12 sample titles; they account for 12 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8907760 UD1 UD
- GSM8907761 UD2 UD
- GSM8907762 UD3 UD
- GSM8907763 D1 D
- GSM8907764 D2 D
- GSM8907765 D3 D
- GSM8907766 UD HF1 UD HF
- GSM8907767 UD HF2 UD HF
- GSM8907768 UD HF3 UD HF
- GSM8907769 D HF1 D HF
- GSM8907770 D HF2 D HF
- GSM8907771 D HF3 D HF
- GSE100303 Histone demethylation and c-MYC activation enhance translational capacity in response to amino acid restriction [RNA-seq] 14 samples shares restriction, amino, acid
- GSE269408 SCGB2A1 deficiency impairs endometrial stromal cell decidualization by decreasing CDK3-mediated proliferation in patients with recurrent implantation failure 10 samples shares decidualization, endometrial, stromal
- GSE246591 Transcriptomic exploration of decidualizing human endometrial stromal cell dynamics 40 samples shares endometrial, stromal
- GSE234338 Extracellular vesicles (EVs) secreted by human aneuploid embryos contain a distinct RNA cargo and upregulate MUC1 transcription in decidualised endometrial stromal cells (dESCs) 32 samples shares endometrial, stromal
- GSE295509 Deciphering ESR1-driven transcription in human endometrial stromal cells via transcriptome, cistrome, and integration with chromatin landscape [ESR1_RNAseq] 12 samples shares endometrial, stromal
- GSE274335 RNA-Seq analysis LPCAT3 knockdown effect on primary human endometrial stromal cells(HESC). 6 samples shares endometrial, stromal
- GSE298658 Transcriptomic profiling of endometrial and dermal mesenchymal stromal cells before and after treatment with menstrual fluid 12 samples shares endometrial, stromal
- GSE246585 Epigenomic exploration of decidualizing human endometrial stromal cell dynamics 40 samples shares endometrial, stromal
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.