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mRNA sequencing on esophageal organoids derived from K5:Smo mice 5 days after tamoxifen injection.

GSE294847 Mus musculus Expression profiling by high throughput sequencing 6 samples Submitted 2026/02/03 Platform GPL24247
Summary
In our study, we used mRNA sequencing to investigate the effect of 3 days-treatment with a combination of TGFb1 and BMP with or without ibuprofen.
Published in
Intrinsic mechanisms and microenvironmental cues fine-tune plasticity of esophageal progenitors
Descampe L, Dassy B, Charara F et al. · Nature communications 2026 · PMID 41862497 · doi:10.1038/s41467-026-70957-4
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Direct links to NCBI, no account and no request form: the whole study as GSE294847_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 6 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1251681 and SRA study SRP579119. Searching any of these in the dataset finder brings you back here.

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