Enhanced Expression of the Female-Biased Gene Gsta2 in Male Proximal Tubule Cells Improves Renal Resilience to Ischemia-Reperfusion Injury
RNA-seq (gene expression) · mouse · 30 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 30 samples: 7 conditions, mostly in duplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE294969_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1252124 and SRA study SRP579468. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 18 samples.
How we read this: 7 replicated groups read from 30 sample titles; they account for 18 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8934260 WT, male, no-surgery
- GSM8934261 WT, male, no-surgery, rep1 WT, male, no-surgery,
- GSM8934262 WT, male, no-surgery, rep2 WT, male, no-surgery,
- GSM8934263 TG, male, no-surgery
- GSM8934264 TG, male, no-surgery, rep1 TG, male, no-surgery,
- GSM8934265 TG, male, no-surgery, rep2 TG, male, no-surgery,
- GSM8934266 WT, Female, no-surgery
- GSM8934267 WT, Female, no-surgery, rep1 WT, Female, no-surgery,
- GSM8934268 WT, Female, no-surgery, rep2 WT, Female, no-surgery,
- GSM8934269 TG, Female, no-surgery
- GSM8934270 TG, Female, no-surgery, rep1 TG, Female, no-surgery,
- GSM8934271 TG, Female, no-surgery, rep2 TG, Female, no-surgery,
- GSM8934272 WT, NX, male
- GSM8934273 TG, NX, male
- GSM8934274 WT, NX, male, rep1
- GSM8934275 TG, NX, male, rep1 TG, NX, male,
- GSM8934276 WT,NX, male, rep2
- GSM8934277 WT, IRI, male
- GSM8934278 TG, IRI, male
- GSM8934279 WT, IRI, male, rep1 WT, IRI, male,
- GSM8934280 TG, IRI,male, rep1
- GSM8934281 WT, IRI,male, rep2
- GSM8934282 TG, NX, male, rep2 TG, NX, male,
- GSM8934283 WT, IRI, male, rep3 WT, IRI, male,
- GSM8934284 TG, IRI, male, rep2 TG, IRI, male,
- GSM8934285 TG, IRI, male, rep3 TG, IRI, male,
- GSM8934286 TG, IRI, male, rep4 TG, IRI, male,
- GSM8934287 TG, IRI, male, rep5 TG, IRI, male,
- GSM8934288 WT, IRI, male, rep4 WT, IRI, male,
- GSM8934289 WT, IRI, male, rep5 WT, IRI, male,
- GSE283374 Dietary methionine deprivation enhances renal resilience against ischemia-reperfusion injury through modulation of glucose oxidation 10 samples shares ischemia-reperfusion, resilience
- GSE260488 Hypidonehydrochloride (YL-0919) improves MCAO-induced ischemia-reperfusion injury by reducing inflammation 9 samples shares ischemia-reperfusion, improves
- GSE280715 Enhanced metabolic resilience and exercise adaptation of skeletal muscle in males by Esr1-induced remodeling of mitochondrial cristae-nucleoid architecture 6 samples shares resilience, enhanced
- GSE254996 ACSS2 upregulation enhances neuronal resilience to aging and neurodegeneration [RNA-seq] 98 samples shares resilience
- GSE311963 CD38 endows local antigen-specific Foxp3+ Treg cells with stress resilience for compartmentalized control of CNS inflammation 68 samples shares resilience
- GSE310244 Dynamic Resilience: Stress Phenotypes and Their Impact on Opioid-Taking Behavior, Brain Activity, and Gene Expression 68 samples shares resilience
- GSE267650 Mouse kidney ischemia-reperfusion injury time course 57 samples shares ischemia-reperfusion
- GSE264100 Resilience to Endoplasmic Reticulum Stress Mitigates Calcium-Dependent Membrane Hyperexcitability Underlying Late Disease Onset in Spinocerebellar Ataxia Type 6 40 samples shares resilience
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.