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Transcriptome profiling of HCT116 cells and differentiated HCT116 cells induced by forced expresssion of MYOD1 or PPARG using RNA-sequencing.

GSE295155 Homo sapiens Expression profiling by high throughput sequencing 3 samples Submitted 2026/06/01 Platform GPL24676
Summary
The core proeprty of cancer cells is neural stemness, which determines tumorigenicity and pluripotency. Therefore, cancer cells can supposedly be induced to differentiate along different lineages. HCT116 is a human colon cancer cell line. We found that HCT116 cells differentiated into muscle- or adipocyte-like cells upon induction by muscle or adipocyte differentiation factor MYOD1 or PPARG, respectively.
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Direct links to NCBI, no account and no request form: the whole study as GSE295155_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 3 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1253636 and SRA study SRP580199. Searching any of these in the dataset finder brings you back here.

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