Conserved Noncoding Cis-Elements Associated with Hibernation Modulate Metabolic and Behavioral Adaptations in Mice [CUT&Run]
ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 14 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Mus musculus (mouse)
- Samples
- 14 samples: 4 × Irx3_cutnrun_Fasted vs 4 × Irx3_cutnrun_Refed12h vs 4 × Irx3_cutnrun_FedGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Conserved noncoding cis elements associated with hibernation modulate metabolic and behavioral adaptations in miceScience (New York, N.Y.) · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE295251_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1243067 and SRA study SRP573804. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 12 samples.
How we read this: 3 replicated groups read from 14 sample titles; they account for 12 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8944303 Irx3_cutnrun_PosCtrl
- GSM8944304 Irx3_cutnrun_Fasted_4 Irx3_cutnrun_Fasted
- GSM8944305 Irx3_cutnrun_Refed12hr_1 Irx3_cutnrun_Refed12h
- GSM8944306 Irx3_cutnrun_Refed12hr_2 Irx3_cutnrun_Refed12h
- GSM8944307 Irx3_cutnrun_Refed12hr_3 Irx3_cutnrun_Refed12h
- GSM8944308 Irx3_cutnrun_Refed12hr_4 Irx3_cutnrun_Refed12h
- GSM8944309 Irx3_cutnrun_NegCtrl
- GSM8944310 Irx3_cutnrun_Fed_1 Irx3_cutnrun_Fed
- GSM8944311 Irx3_cutnrun_Fed_2 Irx3_cutnrun_Fed
- GSM8944312 Irx3_cutnrun_Fed_3 Irx3_cutnrun_Fed
- GSM8944313 Irx3_cutnrun_Fed_4 Irx3_cutnrun_Fed
- GSM8944314 Irx3_cutnrun_Fasted_1 Irx3_cutnrun_Fasted
- GSM8944315 Irx3_cutnrun_Fasted_2 Irx3_cutnrun_Fasted
- GSM8944316 Irx3_cutnrun_Fasted_3 Irx3_cutnrun_Fasted
- GSE295250 Conserved Noncoding Cis-Elements Associated with Hibernation Modulate Metabolic and Behavioral Adaptations in Mice [RNA-seq] 72 samples shares cis-elements, hibernation, adaptations, behavioral, conserved, noncoding, modulate
- GSE304211 H4K16ac contributes to chromatin compartment reorganization during mitotic and meiotic transitions [CUTnTAG] 128 samples shares cut
- GSE297309 SKP1A-mediated degradation of PRC2 triggers activation of Polycomb-silenced gene [CUT&Tag] 108 samples shares cut
- GSE289642 Noncanonical PRC2 chromatin association reveals a key role of EZHIP in intergenerational epigenetic memory transition [ChIP-Seq, Cut & Run] 107 samples shares cut
- GSE303384 Mechanism of maintenance and establishment of repression by the Mtg16 tumor suppressor [CUT&RUN, ChIP-Seq] 92 samples shares cut
- GSE325799 KMT2C and KMT2D amplify GRHL2-driven enhancer activation [CUT&Tag] 80 samples shares cut
- GSE298418 MeCP2 stabilizes the glucocorticoid system in active chromatin regions [CUT&Tag] 63 samples shares cut
- GSE306261 Astrocyte glucocorticoid receptor signaling restricts neuronal plasticity [CUT&RUN] 50 samples shares cut
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.