Lymphatic dysfunction drives inflammatory temporomandibular joint osteoarthritis (TMJOA) and pain
RNA-seq (gene expression) · mouse · 2 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 2 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Identification of Synovial Lymphatics in the TMJ and their Roles in Arthritis and PainResearch square · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE295404_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1254606 and SRA study SRP580842. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 2 more — browse all 2 samples with per-sample file links →
- GSE276088 Single-cell transcriptomic and spatial subcellular landscape of the articular disk synovium in mouse temporomandibular joint osteoarthritis 18 samples shares temporomandibular, osteoarthritis, joint
- GSE303194 Nano MiRNA-Functionating Tetrahedral Framework Nucleic Acid for Cartilage-targeted Ferritinophagy Modulation to Attenuate Temporomandibular Joint Osteoarthritis 15 samples shares temporomandibular, osteoarthritis, joint
- GSE252120 Oxidative stress induced telomere instability/damage drives T cell dysfunction in cancer 32 samples shares dysfunction, drives
- GSE334551 NAD+ Deficiency Drives Metabolic Dysfunction-Associated Atrial Fibrillation 29 samples shares dysfunction, drives
- GSE232098 Innate immune memory after brain injury drives inflammatory cardiac dysfunction 20 samples shares dysfunction, drives
- GSE302245 Locus Coeruleus noradrenergic axon loss drives olfactory dysfunction in Alzheimer's disease 16 samples shares dysfunction, drives
- GSE310612 Astrocytic FABP5 drives cerebellar white matter dysfunction in multiple system atrophy by promoting TNF signaling and ferroptosis 15 samples shares dysfunction, drives
- GSE302342 Lack of cortistatin drives neuroimmune and vascular dysfunction in brain ischemia 14 samples shares dysfunction, drives
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.