DNA Damage-Induced Nuclear STING Translocation Orchestrates Innate Immune Activation and Chromatin Remodeling [ChIP-Seq]
ChIP-seq / ATAC-seq (genome binding and open chromatin) · human · 1 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Homo sapiens (human)
- Samples
- 1 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- DNA damage-induced nuclear STING translocation orchestrates innate immune activation and chromatin remodelingGenes & diseases · 2026
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE296539_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1259940 and SRA study SRP583595. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 1 more — browse all 1 samples with per-sample file links →
- GSE244944 NOTCH1 reverses immune suppression in small cell lung cancer through reactivation of STING [CHIP-seq] 18 samples shares sting, activation, chip-seq
- GSE242372 FACT orchestrates the interplay between chromatin structure and transcription [ChIP-Seq] 16 samples shares orchestrates, chromatin, chip-seq
- GSE303766 Tumor-associated Schwann cell remodeling under metabolic stress via lactate sensing orchestrates [ChIP-seq, MeRIP-seq, RNA-seq] 36 samples shares orchestrates, remodeling, chip-seq
- GSE244403 cGAS-STING axis activation drove inflammatory phenotype acquisition of senescent nucleus pulposus cells via p65-mediated transcriptional modulation 12 samples shares sting, activation
- GSE260486 Fasting boosts breast cancer therapy efficacy via glucocorticoid activation 85 samples shares sting, activation
- GSE307095 RNA-seq profiling of resting naive and CD27bright memory B cells and in vitro activated CD27bright memory B cells reveals differences in B-cell activation patterns in common variable immunodeficiency (CVID) 50 samples shares sting, activation
- GSE318663 Vascular STING activation facilitates NK cell anti-tumor immunity in small cell lung cancer 16 samples shares sting, activation
- GSE324662 Suppression of antiviral innate immunity by the COX2-PGE2-PKA signaling axis by inhibiting the cytosolic mtDNA-dependent activation of STING 12 samples shares sting, activation
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.