GEO series
RNA-seq profiling of resting naive and CD27bright memory B cells and in vitro activated CD27bright memory B cells reveals differences in B-cell activation patterns in common variable immunodeficiency (CVID)
GSE307095
Homo sapiens
Expression profiling by high throughput sequencing
50 samples
2025/12/02
GPL18573
Summary
To investigate the transcriptional differences during resting state and B-cell activation in healthy donors and patients with CVID, we sorted naive B cells and CD27bright memory B cells from the two groups and examined the resting state and TLR9 agonist (CpG)-activated CD27bright memory B cells.
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Paper (PMID 41124223) ↗
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