GEO series
Tomatidine Attenuates Inflammatory Responses to Exercise-Like Stimulation in Donor-derived Skeletal Muscle Myobundles
GSE296683
Homo sapiens
Expression profiling by high throughput sequencing
12 samples
2025/08/27
GPL34281
Summary
We assessed donor-specific response to tomatidine known to inhibit muscle atrophy and promote skeletal muscle hypertrophy. Bioinformatic analyses revealed that infusion of tomatidine during electrical stimulation modulated the IL-6/JAK/STAT3 pathway improving muscle synchronicity in young myobundles compared to those from older volunteers.
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Paper (PMID 40832111) ↗
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