Hereditary Chronic Pancreatitis Induced Plasticity Cooperates with Mutant Kras in Early Pancreatic Carcinogenesis
Single-cell RNA-seq · mouse · 128 samples
- What it is
- Single-cell RNA-seqGene activity measured in thousands of individual cells, so cell types can be told apart. Read from the summary: GEO's own type field only says 'expression profiling by sequencing', so confirm it in the paper.
- Organism
- Mus musculus (mouse)
- Samples
- 128 samples: 120 distinct titles, 4 of them repeatedGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Hereditary chronic pancreatitis induced plasticity cooperates with mutant Kras in early pancreatic carcinogenesisGut · 2026
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE297058_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Single-cell studies usually ship their counts as 10x files (matrix.mtx, barcodes.tsv, features.tsv), an .h5 file, or an .rds / .h5ad object that Seurat or Scanpy can open. Look for those among the supplementary files.
Also filed as BioProject PRJNA1262456 and SRA study SRP584986. Searching any of these in the dataset finder brings you back here.
How we read this: Read from 128 sample titles: 120 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8982767 KC_110266, 8W
- GSM8982768 KC_110270, 8W
- GSM8982769 Cpa1_110465, 8W
- GSM8982770 Cpa1_110466, 8W
- GSM8982771 Cpa1_110463, 8W
- GSM8982772 KCCpa1_110467, 8W
- GSM8982773 KCCpa1_105331, 52W
- GSM8982774 KCCpa1_105568, 52W
- GSM8982775 Cre_111706, 8W
- GSM8982776 Cre_111709, 8W
- GSM8982777 KC_2407241, 15W
- GSM8982778 KCCpa1_240730, 18W
- GSM9000298 KC_65_8, 8 weeks
- GSM9000299 KCRR4, 4 weeks
- GSM9000300 KCL4, 4 weeks
- GSM9000301 KCCPA9994, 4 weeks
- GSM9000302 KCCPA822, 2 weeks
- GSM9000303 KCCPA812, 2 weeks
- GSM9000304 KCCPA60210, 10 weeks
- GSM9000305 KCCPA5958, 8 weeks
- GSM9000306 KCCPA5948, 8 weeks
- GSM9000307 KCCPA5698, 8 weeks
- GSM9000308 KCCPA5678, 8 weeks
- GSM9000309 KCCPA5608, 8 weeks
- GSM9000310 KCCPA54, 4 weeks
- GSM9000311 KCCPA48210, 10 weeks
- GSM9000312 KCCPA47910, 10 weeks
- GSM9000313 KCCPA44, 4 weeks
- GSM9000314 KCCPA44110, 10 weeks
- GSM9000315 KCCPA43910, 10 weeks
- GSM9000316 KCCPA392, 2 weeks
- GSM9000317 KCCPA382, 2 weeks
- GSM9000318 KCCPA34, 4 weeks
- GSM9000319 KCCPA132, 2 weeks
- GSM9000320 KCCPA10004, 4 weeks
- GSM9000321 KC464, 4 weeks
- GSM9000322 KC434, 4 weeks
- GSM9000323 KC424, 4 weeks
- GSM9000324 KC302, 2 weeks
- GSM9000325 KC272, 2 weeks
+ 88 more — browse all 128 samples with per-sample file links →
- GSE328371 KMT2D depletion promote KRAS-induced pancreatic carcinogenesis independent of TP53 24 samples shares carcinogenesis, pancreatic, induced
- GSE252839 Nuclear Factor NFAT5 Governs Cellular Plasticity-Induced KRAS-Targeted Therapy Resistance in Pancreatic Cancer 24 samples shares plasticity, pancreatic, induced
- GSE311286 Analysis of murine normal pancreatic organoids, pancreatitis-derived organoids, and PDAC organoids in complete media and of pancreatitis-derived organoids, and PDAC organoids cultured alone or cocultured with pancreatic stellate cells in reduced media 75 samples shares pancreatitis, pancreatic
- GSE207943 Epigenetic plasticity cooperates with emergent cell-cell interactions to drive neoplastic tissue remodeling in the pancreas 59 samples shares plasticity, cooperates
- GSE87472 The EMT-activator Zeb1 is crucial for cellular plasticity and drives metastasis in pancreatic cancer 36 samples shares plasticity, pancreatic
- GSE270121 Gene expression dynamics in fibroblasts during early-stage murine pancreatic carcinogenesis 34 samples shares carcinogenesis, pancreatic
- GSE287625 Mitochondrial Ca2+ controls pancreatic cancer growth and metastasis by regulating epithelial cell plasticity 18 samples shares plasticity, pancreatic
- GSE285771 Orai1 in pancreatic ductal cells mediates pancreas-intestinal crosstalk in experimental acute pancreatitis via the secretion of antimicrobial peptide REG3B in pancreatic juice 18 samples shares pancreatitis, pancreatic
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.