Prenatal and postnatal effects of gestational immune activation on synaptic and neurodevelopmental pathways via epigenetic mechanisms (RNA-seq)
RNA-seq (gene expression) · mouse · 84 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 84 samples: 42 conditions, mostly in duplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Prenatal and postnatal effects of gestational immune activation on synaptic and neurodevelopmental pathways via epigenetic mechanismsTranslational psychiatry · 2026
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE297245_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1263387 and SRA study SRP585644. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 84 samples.
How we read this: 42 replicated groups read from 84 sample titles; they account for 84 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8986725 GroupA, mouse 1, RNA, replicate 1 GroupA, mouse 1, RNA,
- GSM8986726 GroupA, mouse 1, RNA, replicate 2 GroupA, mouse 1, RNA,
- GSM8986727 GroupA, mouse 2, RNA, replicate 1 GroupA, mouse 2, RNA,
- GSM8986728 GroupA, mouse 2, RNA, replicate 2 GroupA, mouse 2, RNA,
- GSM8986729 GroupA, mouse 3, RNA, replicate 1 GroupA, mouse 3, RNA,
- GSM8986730 GroupA, mouse 3, RNA, replicate 2 GroupA, mouse 3, RNA,
- GSM8986731 GroupA, mouse 4, RNA, replicate 1 GroupA, mouse 4, RNA,
- GSM8986732 GroupA, mouse 4, RNA, replicate 2 GroupA, mouse 4, RNA,
- GSM8986733 GroupA, mouse 5, RNA, replicate 1 GroupA, mouse 5, RNA,
- GSM8986734 GroupA, mouse 5, RNA, replicate 2 GroupA, mouse 5, RNA,
- GSM8986735 GroupA, mouse 6, RNA, replicate 1 GroupA, mouse 6, RNA,
- GSM8986736 GroupA, mouse 6, RNA, replicate 2 GroupA, mouse 6, RNA,
- GSM8986737 GroupB, mouse 1, RNA, replicate 1 GroupB, mouse 1, RNA,
- GSM8986738 GroupB, mouse 1, RNA, replicate 2 GroupB, mouse 1, RNA,
- GSM8986739 GroupB, mouse 2, RNA, replicate 1 GroupB, mouse 2, RNA,
- GSM8986740 GroupB, mouse 2, RNA, replicate 2 GroupB, mouse 2, RNA,
- GSM8986741 GroupB, mouse 3, RNA, replicate 1 GroupB, mouse 3, RNA,
- GSM8986742 GroupB, mouse 3, RNA, replicate 2 GroupB, mouse 3, RNA,
- GSM8986743 GroupB, mouse 4, RNA, replicate 1 GroupB, mouse 4, RNA,
- GSM8986744 GroupB, mouse 4, RNA, replicate 2 GroupB, mouse 4, RNA,
- GSM8986745 GroupB, mouse 5, RNA, replicate 1 GroupB, mouse 5, RNA,
- GSM8986746 GroupB, mouse 5, RNA, replicate 2 GroupB, mouse 5, RNA,
- GSM8986747 GroupB, mouse 6, RNA, replicate 1 GroupB, mouse 6, RNA,
- GSM8986748 GroupB, mouse 6, RNA, replicate 2 GroupB, mouse 6, RNA,
- GSM8986749 GroupC, mouse 1, RNA, replicate 1 GroupC, mouse 1, RNA,
- GSM8986750 GroupC, mouse 1, RNA, replicate 2 GroupC, mouse 1, RNA,
- GSM8986751 GroupC, mouse 2, RNA, replicate 1 GroupC, mouse 2, RNA,
- GSM8986752 GroupC, mouse 2, RNA, replicate 2 GroupC, mouse 2, RNA,
- GSM8986753 GroupC, mouse 3, RNA, replicate 1 GroupC, mouse 3, RNA,
- GSM8986754 GroupC, mouse 3, RNA, replicate 2 GroupC, mouse 3, RNA,
- GSM8986755 GroupC, mouse 4, RNA, replicate 1 GroupC, mouse 4, RNA,
- GSM8986756 GroupC, mouse 4, RNA, replicate 2 GroupC, mouse 4, RNA,
- GSM8986757 GroupC, mouse 5, RNA, replicate 1 GroupC, mouse 5, RNA,
- GSM8986758 GroupC, mouse 5, RNA, replicate 2 GroupC, mouse 5, RNA,
- GSM8986759 GroupC, mouse 6, RNA, replicate 1 GroupC, mouse 6, RNA,
- GSM8986760 GroupC, mouse 6, RNA, replicate 2 GroupC, mouse 6, RNA,
- GSM8986761 GroupD, mouse 1, RNA, replicate 1 GroupD, mouse 1, RNA,
- GSM8986762 GroupD, mouse 1, RNA, replicate 2 GroupD, mouse 1, RNA,
- GSM8986763 GroupD, mouse 2, RNA, replicate 1 GroupD, mouse 2, RNA,
- GSM8986764 GroupD, mouse 2, RNA, replicate 2 GroupD, mouse 2, RNA,
+ 44 more — browse all 84 samples with per-sample file links →
- GSE243942 Spatio-temporal X-linked gene reactivation in the mouse germline reveals site-specific retention of epigenetic silencing [RNA-seq] 125 samples shares activation, epigenetic, rna-seq
- GSE276155 RBBP5 is an epigenetic regulator of mammalian hepatic 12h oscillator [RNA-seq] 96 samples shares epigenetic, rna-seq
- GSE276628 Reciprocal genetic screens identify epigenetics factors controlling epidermal cell activation. [RNAseq_MiniBulk] 41 samples shares activation, epigenetic
- GSE300014 The CARM1 Epigenetic Enzyme Inhibits Cross-presenting Dendritic Cell Function in Cancer Immunity [RNA-seq] 26 samples shares epigenetic, rna-seq
- GSE245648 The Heme-regulated transcriptional repressor, BACH1 safeguards macrophage enhancer selection, activation andtissue adaptation [RNA-seq_BMDM] 24 samples shares activation, rna-seq
- GSE246799 Epigenetic recording of stimulation history reveals BLIMP1-BACH2 balance in determining memory B cell fate upon recall challenge (RNA-Seq) 24 samples shares epigenetic, rna-seq
- GSE227108 Integrated single-cell analysis defines the epigenetic basis of castration-resistant prostate luminal cells (scRNA-seq) 18 samples shares epigenetic, rna-seq
- GSE99296 α-ketoglutarate orchestrates macrophage activation through metabolic and epigenetic reprogramming 18 samples shares activation, epigenetic
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.