Generation of isogenic pluripotent stem cells differing exclusively at two early onset Parkinson point mutations
Expression microarray · human · 18 samples
- What it is
- Expression microarrayGene activity read on a chip (the older technology that RNA-seq replaced).
- Organism
- Homo sapiens (human)
- Samples
- 18 samples: 5 conditions, mostly in duplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed expression table (series matrix) and the array files, from NCBI.
Direct links to NCBI, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need.
Whole study · RAW.tar
Everything the authors deposited as one archive (GSE29774_RAW.tar), including the raw array or instrument files. Can be large; the picker in step 2 takes just the samples you need.
What the files usually look like: For arrays the series matrix is normally the normalised expression table you want; the raw array files (CEL and similar) are in the RAW.tar.
Also filed as BioProject PRJNA141045. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 10 samples.
How we read this: 5 replicated groups read from 18 sample titles; they account for 10 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM738137 WIBR3-IPS-SNCA-A53T(1lox)-6
- GSM738138 WIBR3-IPS-SNCA-A53T-Corr-1
- GSM738139 hESC BGO1
- GSM738140 BGO1-SNCA-A53T/WT
- GSM738141 hESC WIBR3
- GSM738142 WIBR3-SNCA-A53T/WT-1C
- GSM738143 BGO1 replicate 1 BGO1
- GSM738144 BGO1 replicate 2 BGO1
- GSM738145 WIBR3-P39 replicate 1 WIBR3-P39
- GSM738146 WIBR3-P39 replicate 2 WIBR3-P39
- GSM738147 BGO1 SNCA A53T mutation introduced replicate 1 BGO1 SNCA A53T mutation…
- GSM738148 BGO1 SNCA A53T mutation introduced replicate 2 BGO1 SNCA A53T mutation…
- GSM738149 WIBR3 SNCA A53T mutation introduced replicate 1 WIBR3 SNCA A53T mutatio…
- GSM738150 WIBR3 SNCA A53T mutation introduced replicate 2 WIBR3 SNCA A53T mutatio…
- GSM738151 PD patien- derived iPS cell carrying SNCA A53T mutation replicate 1
- GSM738152 PD patient-derived iPS cell carrying SNCA A53T mutation replicate 2
- GSM738153 PD patient-derived iPS cell with SNCA A53T mutation corrected replicate 1 PD patient-derived iPS …
- GSM738154 PD patient-derived iPS cell with SNCA A53T mutation corrected replicate 2 PD patient-derived iPS …
- GSE226482 Single cell RNA sequencing of spinal motor neurons and interneurons differentiated from isogenic FUS and TARDBP human induced pluripotent stem cell lines harbouring ALS-causative mutations 1415 samples shares pluripotent, mutations, isogenic
- GSE269571 Generation of Stable Chambered Cardioids from human Pluripotent Stem Cells [bulk RNA-seq] 24 samples shares pluripotent, generation
- GSE334362 Generation of spermatogonia from human and non-human primate pluripotent stem cells 21 samples shares pluripotent, generation
- GSE324673 Feeder-Free Generation of Lymphatic Endothelial Cells from Human Induced Pluripotent Stem Cells 15 samples shares pluripotent, generation
- GSE332763 Studying the effect of sarcomeric MYH7R663H and non-sarcomeric BRAFT599R hypertrophic cardimyopathy mutations in human induced pluripotent stemm cell-derived cardiomyocytes 15 samples shares pluripotent, mutations
- GSE262419 Informing Hazard Identification and Risk Characterization of Environmental Chemicals by Combining Transcriptomic and Functional Data from Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes 4558 samples shares pluripotent
- GSE309697 Generation of a Comprehensive Epigenomic Atlas in Clear Cell Renal Cell Carcinoma Informs Kidney Cancer Progression and Heritability 265 samples shares generation
- GSE210361 Expression profiling of circular RNAs during differentiation of human pluripotent stem cells into vascular endothelial and smooth muscle cells 160 samples shares pluripotent
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.