Imidazole propionate is an early biomarker and therapeutic target for atherosclerosis [bulk RNA-seq]
RNA-seq (gene expression) · mouse · 27 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 27 samples: 9 conditions, mostly in triplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Imidazole propionate is a driver and therapeutic target in atherosclerosisNature · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE297831_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1266247 and SRA study SRP586892. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 26 samples.
How we read this: 9 replicated groups read from 27 sample titles; they account for 26 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9000564 MAECs, Unstimulated, E1 MAECs, Unstimulated, E
- GSM9000565 MAECs, ImP for 1h, E2 MAECs, ImP for 1h, E
- GSM9000566 MAECs, ImP for 2h, E3 MAECs, ImP for 2h, E
- GSM9000567 MAECs, Unstimulated, E5 MAECs, Unstimulated, E
- GSM9000568 MAECs, ImP for 1h, E6 MAECs, ImP for 1h, E
- GSM9000569 MAECs, ImP for 2h, E7 MAECs, ImP for 2h, E
- GSM9000570 MAECs, Unstimulated, E9 MAECs, Unstimulated, E
- GSM9000571 MAECs, ImP for 1h, E10
- GSM9000572 MAECs, ImP for 2h, E11 MAECs, ImP for 2h, E
- GSM9000573 BMDMs, Unstimulated, M13 BMDMs, Unstimulated, M
- GSM9000574 BMDMs, ImP for 1h, M14 BMDMs, ImP for 1h, M
- GSM9000575 BMDMs, ImP for 2h, M15 BMDMs, ImP for 2h, M
- GSM9000576 BMDMs, Unstimulated, M17 BMDMs, Unstimulated, M
- GSM9000577 BMDMs, ImP for 1h, M18 BMDMs, ImP for 1h, M
- GSM9000578 BMDMs, ImP for 2h, M19 BMDMs, ImP for 2h, M
- GSM9000579 BMDMs, Unstimulated, M21 BMDMs, Unstimulated, M
- GSM9000580 BMDMs, ImP for 1h, M23 BMDMs, ImP for 1h, M
- GSM9000581 BMDMs, ImP for 2h, M22 BMDMs, ImP for 2h, M
- GSM9000582 MEFs, Unstimulated, F25 MEFs, Unstimulated, F
- GSM9000583 MEFs, ImP for 1h, F26 MEFs, ImP for 1h, F
- GSM9000584 MEFs, ImP for 2h, F27 MEFs, ImP for 2h, F
- GSM9000585 MEFs, Unstimulated, F29 MEFs, Unstimulated, F
- GSM9000586 MEFs, ImP for 1h, F30 MEFs, ImP for 1h, F
- GSM9000587 MEFs, ImP for 2h, F31 MEFs, ImP for 2h, F
- GSM9000588 MEFs, Unstimulated, F33 MEFs, Unstimulated, F
- GSM9000589 MEFs, ImP for 1h, F34 MEFs, ImP for 1h, F
- GSM9000590 MEFs, ImP for 2h, F35 MEFs, ImP for 2h, F
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- GSE329323 Establishing Sensory Neurons as Therapeutic Targets in Peripheral Neuropathy Driven by Polyglutamine Expanded ATXN3 [Advil RNA-seq] 18 samples shares therapeutic, rna-seq, target
- GSE308848 Targeting AEBP1 to mitigate pro-tumor activity of cancer-associated fibroblasts and increase therapeutic efficacy to anti-PD-1 [scRNA-Seq] 12 samples shares therapeutic, rna-seq, target
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Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.