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Engineering a Lipid Nanoparticle with Atypical Calcium Crystal Structure for Enhanced IFNβ-mediated Immunotherapy

GSE299449 Mus musculus Expression profiling by high throughput sequencing 4 samples Submitted 2026/06/09 Platform GPL34328
Summary
We have employed a single cell sequencing approach using 10x Genomics scRNAseq to study the anti-tumoral effects of NanoCa. Our results have shown that NanoCa activates the innate immune response by inducing IFNβ, to investigate which types of cells are involved in the anti-tumor effect, CT26 tumor and Tumor-draining lymph nodes were isolated and analyzed using scRNA-seq.
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Direct links to NCBI, no account and no request form: the whole study as GSE299449_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 4 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1274461 and SRA study SRP599676. Searching any of these in the dataset finder brings you back here.

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