GEO series
Methionine metabolism regulates T cell fate by KCa3.1 activity (ATAC-Seq)
GSE299550
Mus musculus
Genome binding/occupancy profiling by high throughput sequencing
12 samples
2025/06/11
GPL24247
Summary
We found that methionine availibility during T cell activation regulates rapid NFAT1 activation, thereby governing T cell fate. Further, acute methionine limitation didn't affect global histone methylation status stating the crucial role of methioinine during early TCR activation.
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Paper (PMID 40702340) ↗
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