GEO series
Transcriptome regulation in T-cells and monocytes in patients with Common Variable Immunodeficiency
GSE299706
Homo sapiens
Expression profiling by high throughput sequencing
20 samples
2026/07/15
GPL18573
Summary
A large subgroup of Common Variable Immunodeficiency (CVID) patients has autoimmune and inflammatory complications, associated with T cell and monocyte pathology, but the molecular mechanism for this CVID-subgroup is still elusive. To identify novel molecular pathways impacted in CVID T cells and monocytes, we examined the transcriptomic profiles in these cells from healthy control and the CVID patients in the subgroup with inflammatory complications.
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Paper (PMID 41991796) ↗
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