GEO series
Resolving inflammation to promote stem cell-based bone regeneration
GSE299815
Mus musculus
Expression profiling by high throughput sequencing
24 samples
2026/03/24
GPL24247
Summary
Bone marrow-derived mesenchymal stromal/stem cells (BMSC) are widely studied for their potential in regenerative therapies for bone defects. However, the therapeutic efficacy of BMSC is strongly influenced by interactions with the host immune system, particularly T lymphocyte subsets. Emerging evidence suggests that while some T cells can impair BMSC-mediated bone healing, regulatory T cells (Treg) may enhance it by promoting a balanced immune environment.
Download
NCBI GEO page ↗
Paper (PMID 41787911) ↗
{# Names what the click gives you. "Open in finder" meant nothing to a
visitor who arrived from a search engine and has never seen the tool. #}
Find more
mouse RNA-seq datasets →
Similar datasets
- GSE292862 Modelling mouse embryogenesis from chemically induced totipotent stem cells 22 samples
- GSE185862 A taxonomy of transcriptomic cell types across the isocortex and hippocampal formation 95 samples
- GSE304862 Semaglutide and exercise synergy in obesity: preserving muscle mass and uncovering organ crosstalk 209 samples
- GSE293315 MRPGRX2 Antagonist Treatment Prevents Inflammation and Disease in a Mouse Model of Atopic Dermatitis Dataset 2 35 samples
- GSE255837 Dysregulation of the Normal Wound Healing Cascade in Volumetric Muscle Loss Injury 30 samples
- GSE341948 Multi-tissue transcriptomic landscape reveals synergistic mechanisms of exercise and GLP-1 agonist in ameliorating diabetic phenotypes in db/db mice 12 samples
- GSE337190 CAR-NKT cells induce low cytokine release syndrome by targeting hyperinflammatory macrophages with mitigation from GM-SCF inhibition. 24 samples
- GSE306116 Caspase-3 Control of RNA Splicing and Mitochondrial Dynamics in Microglia during Parkinson’s Disease [RNA-Seq] 12 samples
Share this dataset
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.