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Organoid modeling of lung branching morphogenesis and epithelial lineage specification [scRNA-Seq]

GSE300724 Mus musculus Expression profiling by high throughput sequencing 6 samples Submitted 2026/06/23 Platform GPL34290
Summary
In this study, multi-level branching lung organoids (BLOs) were generated from primary tip epithelial cells. Single-cell RNA sequencing demonstrated that BLOs comprise proximal airway and distal alveolar epithelial cell populations, faithfully modeling the developmental trajectory of distal lung epithelial lineages in vitro.
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Direct links to NCBI, no account and no request form: the whole study as GSE300724_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 6 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1281910 and SRA study SRP594488. Searching any of these in the dataset finder brings you back here.

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