Control and Tgfbr2 cKO Mouse Endometrial Epithelial Organoids +/- E2/MPA Treatment
RNA-seq (gene expression) · mouse · 16 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 16 samples: 16 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- TGFBR2 coordinates the endometrial response to estrogen, regulating endometrial hyperplasia and fertilityProceedings of the National Academy of Sciences of the United States of America · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE301156_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1284210 and SRA study SRP596007. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 16 sample titles: 16 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9076466 M1 control veh
- GSM9076467 M2 control veh
- GSM9076468 M3 control veh
- GSM9076469 M4 control veh
- GSM9076470 M5 Tgfbr2 cKO veh
- GSM9076471 M6 Tgfbr2 cKO veh
- GSM9076472 M7 Tgfbr2 cKO veh
- GSM9076473 M8 Tgfbr2 cKO veh
- GSM9076474 M9 control E2/MPA
- GSM9076475 M10 control E2/MPA
- GSM9076476 M11 control E2/MPA
- GSM9076477 M12 control E2/MPA
- GSM9076478 M13 Tgfbr2 cKO E2/MPA
- GSM9076479 M14 Tgfbr2 cKO E2/MPA
- GSM9076480 M15 Tgfbr2 cKO E2/MPA
- GSM9076481 M16 Tgfbr2 cKO E2/MPA
- GSE311963 CD38 endows local antigen-specific Foxp3+ Treg cells with stress resilience for compartmentalized control of CNS inflammation 68 samples shares mpa, control
- GSE283201 Comparative gene expression profiling analysis of hippocampus and liver RNA-seq data for young (3-month-old) and aged (22-month-old) WT mice in both control and ethanol feeding conditions. 32 samples shares mpa, control
- GSE328496 Gene expression + ATAC profiling of trisomic hippocampal neurons upon SAHA treatment [RNA-seq] 16 samples shares mpa, treatment
- GSE274650 G3BP1 translocates into mitochondria to impair MCU complex function and promotes NASH progression [G3bp1-HKO and G3bp1-Flox mice with BSA or PA treatment] 12 samples shares mpa, treatment
- GSE286094 Loss of ATG7 in Microglia Impairs UPR, Triggers Ferroptosis and Weakens Amyloid Pathology Control [scRNA-seq] 11 samples shares mpa, control
- GSE312105 Assessing the impact of epigenetic inhibitors on reversion of the chromatin landscape from metastatic to non-metastatic organoids 18 samples shares mpa, organoids
- GSE328495 Gene expression + ATAC profiling of trisomic hippocampal neurons upon SAHA treatment [ATAC-seq] 16 samples shares mpa, treatment
- GSE287625 Mitochondrial Ca2+ controls pancreatic cancer growth and metastasis by regulating epithelial cell plasticity 18 samples shares epithelial, control
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.