Effects of Gestational and Lactational Exposure to Perfluorohexanoic Acid on the cerebellar transcriptome
RNA-seq (gene expression) · mouse · 34 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 34 samples: 6 conditions, mostly with about 6 replicates eachGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Gestational and Lactation Exposure to Perfluorohexanoic Acid Results in Sex-Specific Changes in the Cerebellum in MiceInternational journal of molecular sciences · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE301375_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1284876 and SRA study SRP596425. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 34 samples.
How we read this: 6 replicated groups read from 34 sample titles; they account for 34 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9081768 higher, male, rep1 higher, male,
- GSM9081769 higher, female, rep1 higher, female,
- GSM9081770 lower, male, rep1 lower, male,
- GSM9081771 lower, female, rep1 lower, female,
- GSM9081772 control, male, rep1 control, male,
- GSM9081773 control , female, rep1 control , female,
- GSM9081774 control, male, rep2 control, male,
- GSM9081775 control , female, rep2 control , female,
- GSM9081776 higher, male, rep2 higher, male,
- GSM9081777 higher, female, rep2 higher, female,
- GSM9081778 lower, male, rep2 lower, male,
- GSM9081779 lower, female, rep2 lower, female,
- GSM9081780 higher, male, rep3 higher, male,
- GSM9081781 higher, female, rep3 higher, female,
- GSM9081782 lower, male, rep3 lower, male,
- GSM9081783 lower, female, rep3 lower, female,
- GSM9081784 control, male, rep3 control, male,
- GSM9081785 control , female, rep3 control , female,
- GSM9081786 lower, male, rep4 lower, male,
- GSM9081787 lower, female, rep4 lower, female,
- GSM9081788 higher, male, rep4 higher, male,
- GSM9081789 higher, female, rep4 higher, female,
- GSM9081790 control, male, rep4 control, male,
- GSM9081791 control , female, rep4 control , female,
- GSM9081792 control, male, rep5 control, male,
- GSM9081793 control , female, rep5 control , female,
- GSM9081794 lower, male, rep5 lower, male,
- GSM9081795 lower, female, rep5 lower, female,
- GSM9081796 higher, male, rep5 higher, male,
- GSM9081797 higher, female, rep5 higher, female,
- GSM9081798 higher, male, rep6 higher, male,
- GSM9081799 higher, female, rep6 higher, female,
- GSM9081800 lower, male, rep6 lower, male,
- GSM9081801 lower, female, rep6 lower, female,
- GSE252250 Glucocorticoid receptor-dependent therapeutic efficacy of tauroursodeoxycholic acid in preclinical models of Spinocerebellar ataxia type 3 9 samples shares cerebellar, acid
- GSE261095 Gestational Exposure to Air Pollutants Perturbs Metabolic and Placenta-Fetal Phenotype 9 samples shares gestational, exposure
- GSE241770 ACSS2 mediates an epigenetic pathway to regulate maternal Beta-cell adaptation and progression of gestational diabetes (scRNA-Seq) 7899 samples shares gestational
- GSE297245 Prenatal and postnatal effects of gestational immune activation on synaptic and neurodevelopmental pathways via epigenetic mechanisms (RNA-seq) 84 samples shares gestational
- GSE260623 Germline ELP1 deficiency sensitizes cerebellar granule neuron progenitors to SHH medulloblastoma [bulkRNA] 91 samples shares cerebellar
- GSE255633 Region-specific pathogenesis and dissipation of intraregional heterogeneity in cerebellar neurodegeneration 49 samples shares cerebellar
- GSE264100 Resilience to Endoplasmic Reticulum Stress Mitigates Calcium-Dependent Membrane Hyperexcitability Underlying Late Disease Onset in Spinocerebellar Ataxia Type 6 40 samples shares cerebellar
- GSE271392 Transcriptomic profiling of medulla and cervical spinal cord to study respiratory neuropathology in Spinocerebellar ataxia type 7 35 samples shares cerebellar
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.