Polysome seq of treated with Enzalutamide and untreated (DMSO)prostate cancer cell line with SPEN wt and SPEN KO
RNA-seq (gene expression) · human · 30 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Topic
- Prostate cancerThis series is part of our curated briefing on it.
- Samples
- 30 samples: 10 conditions, mostly in triplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE301583_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1285687 and SRA study SRP598013. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 30 samples.
How we read this: 10 replicated groups read from 30 sample titles; they account for 30 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9085860 Enzalutamide SPEN WT RNA 1 Enzalutamide SPEN WT RNA
- GSM9085861 Enzalutamide SPEN WT RNA 2 Enzalutamide SPEN WT RNA
- GSM9085862 Enzalutamide SPEN WT RNA 3 Enzalutamide SPEN WT RNA
- GSM9085863 Enzalutamide SPEN KO RNA 1 Enzalutamide SPEN KO RNA
- GSM9085864 Enzalutamide SPEN KO RNA 2 Enzalutamide SPEN KO RNA
- GSM9085865 Enzalutamide SPEN KO RNA 3 Enzalutamide SPEN KO RNA
- GSM9085866 DMSO SPEN WT RNA 1 DMSO SPEN WT RNA
- GSM9085867 DMSO SPEN WT RNA 2 DMSO SPEN WT RNA
- GSM9085868 DMSO SPEN WT RNA 3 DMSO SPEN WT RNA
- GSM9085869 DMSO SPEN KO RNA 1 DMSO SPEN KO RNA
- GSM9085870 DMSO SPEN KO RNA 2 DMSO SPEN KO RNA
- GSM9085871 DMSO SPEN KO RNA 3 DMSO SPEN KO RNA
- GSM9085872 Enzalutamide SPEN WT 80S 1 Enzalutamide SPEN WT 80S
- GSM9085873 Enzalutamide SPEN WT lowpoly 1 Enzalutamide SPEN WT lo…
- GSM9085874 Enzalutamide SPEN WT highpoly 1 Enzalutamide SPEN WT hi…
- GSM9085875 Enzalutamide SPEN WT 80S 2 Enzalutamide SPEN WT 80S
- GSM9085876 Enzalutamide SPEN WT lowpoly 2 Enzalutamide SPEN WT lo…
- GSM9085877 Enzalutamide SPEN WT highpoly 2 Enzalutamide SPEN WT hi…
- GSM9085878 Enzalutamide SPEN WT 80S 3 Enzalutamide SPEN WT 80S
- GSM9085879 Enzalutamide SPEN WT lowpoly 3 Enzalutamide SPEN WT lo…
- GSM9085880 Enzalutamide SPEN WT highpoly 3 Enzalutamide SPEN WT hi…
- GSM9085881 Enzalutamide SPEN KO 80S 1 Enzalutamide SPEN KO 80S
- GSM9085882 Enzalutamide SPEN KO lowpoly 1 Enzalutamide SPEN KO lo…
- GSM9085883 Enzalutamide SPEN KO highpoly 1 Enzalutamide SPEN KO hi…
- GSM9085884 Enzalutamide SPEN KO 80S 2 Enzalutamide SPEN KO 80S
- GSM9085885 Enzalutamide SPEN KO lowpoly 2 Enzalutamide SPEN KO lo…
- GSM9085886 Enzalutamide SPEN KO highpoly 2 Enzalutamide SPEN KO hi…
- GSM9085887 Enzalutamide SPEN KO 80S 3 Enzalutamide SPEN KO 80S
- GSM9085888 Enzalutamide SPEN KO lowpoly 3 Enzalutamide SPEN KO lo…
- GSM9085889 Enzalutamide SPEN KO highpoly 3 Enzalutamide SPEN KO hi…
- GSE120181 Human prostate cancer cell line, 22Rv1: Control vs. luteolin treatment 2 samples same disease briefing · shares prostate, line
- GSE115501 RNA sequencing on circulating tumor cells from prostate cancer patients 136 samples same disease briefing · shares prostate
- GSE222467 The RNA binding proteins LARP4A and LARP4B promote tumour growth and metastasis in prostate cancer and osteosarcoma 12 samples same disease briefing · shares prostate
- GSE300947 A novel six-biomarker panel identified from male breast cancer-associated fibroblasts demonstrates prognostic power for prostate tumors 6 samples same disease briefing · shares prostate
- GSE242541 ONECUT2 is a druggable driver of luminal to basal breast cancer plasticity 12 samples same disease briefing
- GSE71008 Plasma extracellular RNA profiles in healthy and cancer patients 192 samples same disease briefing
- GSE215340 RNAseq data for COV362 and PEO1 cell lines treated with DMSO (vehicle) or Prexasertib 20 nM 12 samples shares dmso, treated, line
- GSE168618 Whole transcriptomes analyses of HGC-27 cell line treated with control DMSO, disulfiram, thiram or CX-6258 4 samples shares dmso, treated, line
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.