Deletion of Trdn-as or Mettl3 transcription in the adult heart
ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 18 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Mus musculus (mouse)
- Samples
- 18 samples: 6 conditions, mostly in duplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE301905_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1287713 and SRA study SRP599053. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 12 samples.
How we read this: 6 replicated groups read from 18 sample titles; they account for 12 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9092109 Ctcf-ko-Mettl3_1 Ctcf-ko-Mettl3
- GSM9092110 Ctcf-ko-Mettl3_2 Ctcf-ko-Mettl3
- GSM9092111 Ctcf-ko-Trdn_1 Ctcf-ko-Trdn
- GSM9092112 Ctcf-ko-Trdn_2 Ctcf-ko-Trdn
- GSM9092113 Ctcf-WT_1 Ctcf-WT
- GSM9092114 Ctcf-WT_2 Ctcf-WT
- GSM9092115 Polr2a-WT_1 Polr2a-WT
- GSM9092116 Polr2a-WT_2 Polr2a-WT
- GSM9092117 Polr2a-ko-Mettl3_1 Polr2a-ko-Mettl3
- GSM9092118 Polr2a-ko-Mettl3_2 Polr2a-ko-Mettl3
- GSM9092119 Polr2a-ko-Trdn_1 Polr2a-ko-Trdn
- GSM9092120 Polr2a-ko-Trdn_2 Polr2a-ko-Trdn
- GSM9092121 IgG-WT_1
- GSM9092122 IgG-ko-Mettl3_1
- GSM9092123 IgG-ko-Trdn_1
- GSM9092124 WT_1_input
- GSM9092125 ko-Mettl3_1_input
- GSM9092126 ko-Trdn_1_input
- GSE237643 Deletion of the mRNA endonuclease Regnase-1 promotes NK cell anti-tumor activity via OCT2- dependent transcription of Ifng 58 samples shares transcription, deletion
- GSE150817 Transcriptional dynamics of the murine heart during perinatal development at single-cell resolution 30 samples shares transcription, heart
- GSE279796 Setdb1 regulates proper differentiation of adult intestinal stem cells via restraining permissive chromatin structure and transcriptional variability 18 samples shares transcription, adult
- GSE215759 Mettl3-dependent m6A modification is essential for effector differentiation and memory formation of CD8+ T cells [RNA-seq] 15 samples shares mettl3
- GSE315612 Yiqi Huoxue Yangyin Decoction alleviates diabetic nephropathy by attenuating podocyte injury via the METTL3-m6A-mTOR pathway to activate autophagy 12 samples shares mettl3
- GSE252044 METTL3 in Diabetic Cardiomyopathy 11 samples shares mettl3
- GSE283958 Cohesin recruitment to promoters and enhancers by general transcription factors and chromatin regulators 47 samples shares transcription
- GSE268172 Stable maintenance of MERVL-positive embryonic stem cells reveals sustained transcriptional programs and enhancer remodeling 45 samples shares transcription
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.