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Single-nucleus RNA sequencing of the cerebral cortex in Gclc knockout mice at 3 and 6 months of age

GSE301920 Mus musculus Expression profiling by high throughput sequencing 4 samples Submitted 2025/07/23 Platform GPL24247
Summary
This study investigates the transcriptomic impact of glutamate–cysteine ligase catalytic subunit (Gclc) deficiency in the mouse cortex at 3 and 6 months of age using single-nucleus RNA sequencing.
Published in
Rod-shaped microglia represent a morphologically distinct subpopulation of disease-associated microglia
Matsuba Y, Nagata K, Kadota Y et al. · Journal of neuroinflammation 2025 · PMID 40671004 · doi:10.1186/s12974-025-03504-5
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Direct links to NCBI, no account and no request form: the whole study as GSE301920_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 4 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1286132 and SRA study SRP598289. Searching any of these in the dataset finder brings you back here.

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