GEO series

Biological processes in hind paws, dorsal root ganglia and spinal cord after PTX treatment (the short model)

GSE302112 Mus musculus (mouse) RNA-seq (gene expression) 51 samples Submitted 2026/03/02 Platform GPL21493

At a glance

RNA-seq (gene expression) · mouse · 51 samples

What it is: RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
Organism: Mus musculus (mouse)
Samples: 51 samples: 17 conditions, mostly in triplicateGroups are read from the sample names, not from the paper. Check the list below.
Data you can get: A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.

Summary (written by the submitters)

We investigated biological processes in hind paw, dorsal root ganglion (DRG) and spinal cord (SC) associated with chemotherapy treatment.

This dataset

Open GSE302112 in finder → Find more mouse RNA-seq datasets →

Download · which file do I need?

Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.

1 · Just have a look

Processed table

The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.

Series matrix ↓

2 · Re-analyse it

Supplementary files

The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE302112_RAW.tar (it can run to tens of gigabytes).

All supplementary files ↗ Whole study · RAW.tar ↓

3 · Start from the raw reads

Raw sequencing reads

The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.

Raw reads on ENA ↗

What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.

Also filed as BioProject PRJNA1288543 and SRA study SRP599259. Searching any of these in the dataset finder brings you back here.

NCBI GEO page ↗

Study design

17 conditions, mostly in triplicate

PTX 2 days post-ptx D# ×3 PTX CONTROL 2 days post-ptx D# ×3 PTX 2 days post-ptx P# ×3 PTX CONTROL 2 days post-ptx P# ×3 PTX 7 days post-ptx D# ×3 PTX 7 days post-ptx P# ×3 PTX 22 days post-ptx D# ×3 PTX 22 days post-ptx P# ×3 +9 more

Supports a between-group comparison across 51 samples.

How we read this: 17 replicated groups read from 51 sample titles; they account for 51 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.

Samples in this study

GSM9096427 PTX 2 days post-ptx D#1 PTX 2 days post-ptx D#
GSM9096428 PTX 2 days post-ptx D#2 PTX 2 days post-ptx D#
GSM9096429 PTX 2 days post-ptx D#3 PTX 2 days post-ptx D#
GSM9096430 PTX CONTROL 2 days post-ptx D#1 PTX CONTROL 2 days post…
GSM9096431 PTX CONTROL 2 days post-ptx D#2 PTX CONTROL 2 days post…
GSM9096432 PTX CONTROL 2 days post-ptx D#3 PTX CONTROL 2 days post…
GSM9096433 PTX 2 days post-ptx P#1 PTX 2 days post-ptx P#
GSM9096434 PTX 2 days post-ptx P#2 PTX 2 days post-ptx P#
GSM9096435 PTX 2 days post-ptx P#3 PTX 2 days post-ptx P#
GSM9096436 PTX CONTROL 2 days post-ptx P#1 PTX CONTROL 2 days post…
GSM9096437 PTX CONTROL 2 days post-ptx P#2 PTX CONTROL 2 days post…
GSM9096438 PTX CONTROL 2 days post-ptx P#3 PTX CONTROL 2 days post…
GSM9096439 PTX 7 days post-ptx D#1 PTX 7 days post-ptx D#
GSM9096440 PTX 7 days post-ptx D#2 PTX 7 days post-ptx D#
GSM9096441 PTX 7 days post-ptx D#3 PTX 7 days post-ptx D#
GSM9096442 PTX 7 days post-ptx P#1 PTX 7 days post-ptx P#
GSM9096443 PTX 7 days post-ptx P#2 PTX 7 days post-ptx P#
GSM9096444 PTX 7 days post-ptx P#3 PTX 7 days post-ptx P#
GSM9096445 PTX 22 days post-ptx D#1 PTX 22 days post-ptx D#
GSM9096446 PTX 22 days post-ptx D#2 PTX 22 days post-ptx D#
GSM9096447 PTX 22 days post-ptx D#3 PTX 22 days post-ptx D#
GSM9096448 PTX 22 days post-ptx P#1 PTX 22 days post-ptx P#
GSM9096449 PTX 22 days post-ptx P#2 PTX 22 days post-ptx P#
GSM9096450 PTX 22 days post-ptx P#3 PTX 22 days post-ptx P#
GSM9096451 PTX 7 days ipsi #1 PTX 7 days ipsi #
GSM9096452 PTX 7 days ipsi #2 PTX 7 days ipsi #
GSM9096453 PTX 7 days ipsi #3 PTX 7 days ipsi #
GSM9096454 PTX 7 days control #1 PTX 7 days control #
GSM9096455 PTX 7 days control #2 PTX 7 days control #
GSM9096456 PTX 7 days control #3 PTX 7 days control #
GSM9096457 PTX 1 day ipsi #1 PTX 1 day ipsi #
GSM9096458 PTX 1 day ipsi #2 PTX 1 day ipsi #
GSM9096459 PTX 1 day ipsi #3 PTX 1 day ipsi #
GSM9096460 PTX 1 day control #1 PTX 1 day control #
GSM9096461 PTX 1 day control #2 PTX 1 day control #
GSM9096462 PTX 1 day control #3 PTX 1 day control #
GSM9096463 PTX – 1 day post ptx IP S#1 PTX – 1 day post ptx IP…
GSM9096464 PTX – 1 day post ptx IP S#2 PTX – 1 day post ptx IP…
GSM9096465 PTX – 1 day post ptx IP S#3 PTX – 1 day post ptx IP…
GSM9096466 PTX – 22 days post ptx IP S#1 PTX – 22 days post ptx …

+ 11 more — browse all 51 samples with per-sample file links →

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Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.