GEO series
PFOS perturbs mitochondrial metabolism in skeletal muscle in vivo
GSE302489
Mus musculus
Expression profiling by high throughput sequencing
48 samples
2025/08/01
GPL24247
Summary
The purpose of this project was to investigate the effects of PFOS on skeletal muscle in vivo. To perform this work, Cyp2b-null and hCYP2B6-Tg mice were treated with 0, 1, or 10 mg/kg/day PFOS for 21 days. Gastrocnemius muscle was collected during necropsy and various assays were performed. RNA seq was performed to determine what gene expression changes occured due to PFOS treatment and the difference between genotypes.
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Paper (PMID 41475119) ↗
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