GEO series

Expression analysis of 52 glioma clinical samples (36 CIMP+ and 16 CIMP-) and 6 cell line samples

GSE30336 Homo sapiens Expression profiling by array 58 samples Submitted 2012/02/16 Platform GPL571Platform GPL570

Summary

Glioma CIMP (G-CIMP) is a powerful determinant of tumor pathogenicity but the molecular cause of G-CIMP is a fundamental question that is unresolved. Here, we show that mutation of a single gene, isocitrate dehydrogenase 1 (IDH1), directly causes the G-CIMP in gliomas by remodeling the methylome.

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Direct links to NCBI, no account and no request form: the whole study as GSE30336_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 58 samples.

Whole study · RAW.tar ↓ Series matrix ↓ All supplementary files ↗

Also filed as BioProject PRJNA154809. Searching any of these in the dataset finder brings you back here.

NCBI GEO page ↗ Paper (PMID 22343889) ↗

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