A tumor-associated macrophage-targeted immunocytokine leveraging T and NK cell synergy for potent cancer immunotherapy
RNA-seq (gene expression) · mouse · 223 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 223 samples: 193 distinct titles, 6 of them repeatedGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Macrophage-targeted immunocytokine leverages myeloid, T, and NK cell synergy for cancer immunotherapyCell · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE303870_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1298090 and SRA study SRP601116. Searching any of these in the dataset finder brings you back here.
How we read this: Read from 223 sample titles: 193 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9109273 AB15396.txt
- GSM9109274 AB15397.txt
- GSM9109275 AB15398.txt
- GSM9109276 AB15399.txt
- GSM9109277 AB15400.txt
- GSM9109278 AB15401.txt
- GSM9109279 AB15402.txt
- GSM9109280 AB15403.txt
- GSM9109281 AB15404.txt
- GSM9109282 AB15405.txt
- GSM9109283 AB15406.txt
- GSM9109284 AB15407.txt
- GSM9109285 AB15408.txt
- GSM9109286 AB15409.txt
- GSM9109287 AB15410.txt
- GSM9109288 AB15411.txt
- GSM9109289 AB15412.txt
- GSM9109290 AB15413.txt
- GSM9109291 AB15414.txt
- GSM9109292 AB15415.txt
- GSM9109293 AB15416.txt
- GSM9109294 AB15417.txt
- GSM9109295 AB15418.txt
- GSM9109296 AB15419.txt
- GSM9109297 AB15420.txt
- GSM9109298 AB15421.txt
- GSM9109299 AB15422.txt
- GSM9109300 AB15423.txt
- GSM9109301 AB15424.txt
- GSM9109302 AB15425.txt
- GSM9109303 AB15426.txt
- GSM9109304 AB15427.txt
- GSM9109305 AB15428.txt
- GSM9109306 AB15429.txt
- GSM9109307 AB15430.txt
- GSM9109308 AB15431.txt
- GSM9109309 AB15432.txt
- GSM9109310 AB15433.txt
- GSM9109311 AB15434.txt
- GSM9109312 AB15435.txt
+ 183 more — browse all 223 samples with per-sample file links →
- GSE292179 Priming with DNMT inhibitors potentiates PD-1 immunotherapy by triggering viral mimicry in relapsed/refractory NK/T-cell lymphoma 14 samples shares immunotherapy, potent
- GSE314854 Targeting Modulated Vascular Smooth Muscle Cells in Atherosclerosis via FAP-Directed Immunotherapy 102 samples shares immunotherapy
- GSE295309 Microbial cancer immunotherapy reprograms hematopoiesis to enhance myeloid-driven anti-tumor immunity 39 samples shares immunotherapy
- GSE316054 Targeting the ADAR1 p150 isoform triggers tumor growth inhibition and antitumor immunity to overcome immunotherapy resistance 52 samples shares immunotherapy
- GSE307471 Intratumoral bacteria are immunosuppressive and promote immunotherapy resistance in head and neck squamous cell carcinoma 33 samples shares immunotherapy
- GSE228550 Reversing myeloid-derived suppressor cells mediated immunosuppression via p38α inhibition enhances immunotherapy efficacy 12 samples shares immunotherapy
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.