Decoupling oxidative resilience from reprogramming to rejuvenate the RPE and restore vision
ChIP-seq / ATAC-seq (genome binding and open chromatin) · human · 120 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Homo sapiens (human)
- Samples
- 120 samples: 24 conditions, mostly with about 4 replicates eachGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE304044_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1298805 and SRA study SRP604608. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 120 samples.
How we read this: 24 replicated groups read from 120 sample titles; they account for 120 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9141432 3-months-rep1 3-months
- GSM9141433 3-months-rep2 3-months
- GSM9141434 3-months-rep3 3-months
- GSM9141435 3-months-rep4 3-months
- GSM9141436 15-months-rep1 15-months
- GSM9141437 15-months-rep2 15-months
- GSM9141438 15-months-rep3 15-months
- GSM9141439 15-months-rep4 15-months
- GSM9141440 15-months-rep5 15-months
- GSM9141441 24-months-rep1 24-months
- GSM9141442 24-months-rep2 24-months
- GSM9141443 24-months-rep3 24-months
- GSM9141444 24-months-rep4 24-months
- GSM9141445 24-months-rep5 24-months
- GSM9141446 3-months-OSK-rep1 3-months-OSK
- GSM9141447 3-months-OSK-rep2 3-months-OSK
- GSM9141448 3-months-OSK-rep3 3-months-OSK
- GSM9141449 3-months-OSK-rep4 3-months-OSK
- GSM9141450 15-months-OSK-rep1 15-months-OSK
- GSM9141451 15-months-OSK-rep2 15-months-OSK
- GSM9141452 15-months-OSK-rep3 15-months-OSK
- GSM9141453 15-months-OSK-rep4 15-months-OSK
- GSM9141454 15-months-OSK-rep5 15-months-OSK
- GSM9141455 24-months-OSK-rep1 24-months-OSK
- GSM9141456 24-months-OSK-rep2 24-months-OSK
- GSM9141457 24-months-OSK-rep3 24-months-OSK
- GSM9141458 24-months-OSK-rep4 24-months-OSK
- GSM9141459 24-months-OSK-rep5 24-months-OSK
- GSM9141460 3-months-OSK-onoff-rep1 3-months-OSK-onoff
- GSM9141461 3-months-OSK-onoff-rep2 3-months-OSK-onoff
- GSM9141462 3-months-OSK-onoff-rep3 3-months-OSK-onoff
- GSM9141463 3-months-OSK-onoff-rep4 3-months-OSK-onoff
- GSM9141464 15-months-OSK-onoff-rep1 15-months-OSK-onoff
- GSM9141465 15-months-OSK-onoff-rep2 15-months-OSK-onoff
- GSM9141466 15-months-OSK-onoff-rep3 15-months-OSK-onoff
- GSM9141467 15-months-OSK-onoff-rep4 15-months-OSK-onoff
- GSM9141468 15-months-OSK-onoff-rep5 15-months-OSK-onoff
- GSM9141469 24-months-OSK-onoff-rep1 24-months-OSK-onoff
- GSM9141470 24-months-OSK-onoff-rep2 24-months-OSK-onoff
- GSM9141471 24-months-OSK-onoff-rep3 24-months-OSK-onoff
+ 80 more — browse all 120 samples with per-sample file links →
- GSE271447 Myocardial Reprogramming by HMGN1 Underlies Heart Defects in Trisomy 21 84 samples shares reprogramming
- GSE43916 Hierarchical mechanisms for transcription factor-mediated reprogramming of fibroblasts to neurons 38 samples shares reprogramming
- GSE291280 Cardiac Radiotherapy-Induced Epigenetic Memory Underlies Electrophysiologic and Metabolic Reprogramming [RNA-seq] 108 samples shares reprogramming
- GSE279644 BCR::ABL1-induced enhancer reprogramming uncovers hypersensitivity of Ph+B-ALL cells to enhancer-targeting drugs [ChIP-Seq] 91 samples shares reprogramming
- GSE99284 Enhancer reprogramming promotes pancreatic cancer progression and metastasis [ChIP-seq] 90 samples shares reprogramming
- GSE270779 MYC couples SWI/SNF and metabolic reprogramming to sustain minimal residual disease in mTORC1-activated cancer cells 64 samples shares reprogramming
- GSE279594 BCR::ABL1-induced enhancer reprogramming uncovers hypersensitivity of Ph+B-ALL cells to enhancer-targeting drugs [RNA-Seq] 52 samples shares reprogramming
- GSE115462 TP63-mediated enhancer reprogramming drives the squamous subtype of pancreatic ductal adenocarcinoma (RNA-seq) 42 samples shares reprogramming
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.