Expression profiling of THP-1 cells with and without infection by Francisella tularensis and with or without treatment with Dillapiole
RNA-seq (gene expression) · human · 20 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 20 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Dillapiole Dampens the Expression of the Major Virulence Genes of Francisella tularensisMolecules (Basel, Switzerland) · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE306199_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1309670 and SRA study SRP610735. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 20 more — browse all 20 samples with per-sample file links →
- GSE292594 THP-1 infection H37Rv sequencing results [1,25(OH)2D3 treatment] 4 samples shares thp-1, treatment
- GSE149809 Transcriptomic responses to a live-attenuated Francisella tularensis vaccine 100 samples shares francisella, tularensis
- GSE292593 THP-1 infection H37Rv sequencing results 6 samples shares thp-1
- GSE12108 Microarray analysis of human monocytes infected with Francisella tularensis 14 samples shares francisella, tularensis
- GSE313992 Comparative Immunotoxicity and Transcriptomic Profiling of Seven PFAS in THP-1 Macrophages 252 samples shares thp-1
- GSE281531 Effect of depletion of MALAT1 on gene expression during LPS stimulation on THP-1 derived differentiated macrophages 24 samples shares thp-1
- GSE278567 Effect of the rhesus theta defensin-1 (RTD-1) on gene expression in human monocytic THP-1 cells. [I] 24 samples shares thp-1
- GSE269185 Effect of decitabine on gene expression in THP-1 or decitabine-resistant THP-1 leukemia cells 8 samples shares thp-1
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.