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Single-cell RNA-seq of immune and stromal cells from murine muscle injury and foreign body response to synthetic biomaterial implants

GSE306253 Mus musculus Expression profiling by high throughput sequencing 3 samples Submitted 2026/03/11 Platform GPL24247
Summary
The main objective of this study is to characterize the immune and stromal cell response to tissue injury and the foreign body response (synthetic polycaprolactone PCL implant). We enrich CD45+ immune cells from injured murine muscles with fibrotic PCL implants (6 week time point) and perform transcriptomic profile using single-cell RNA-sequencing.
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Direct links to NCBI, no account and no request form: the whole study as GSE306253_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 3 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1310296 and SRA study SRP612227. Searching any of these in the dataset finder brings you back here.

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