Developmental trajectory of the mouse transcriptome following placental allopregnanolone insufficiency in the somatosensosry cortex, hippocampus and cerebellum
RNA-seq (gene expression) · mouse · 175 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 175 samples: 44 conditions, mostly with about 4 replicates eachGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Microglia alter sex-specific cerebellar myelination following placental hormone lossNature communications · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE306583_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1311349 and SRA study SRP613457. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 175 samples.
How we read this: 44 replicated groups read from 175 sample titles; they account for 175 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9204066 Cerebellum, Female, P7, KO, replicate 1 Cerebellum, Female, P7,…
- GSM9204067 Cerebellum, Male, P7, WT, replicate 1 Cerebellum, Male, P7, W…
- GSM9204068 Cerebellum, Female, P7, KO, replicate 2 Cerebellum, Female, P7,…
- GSM9204069 Cerebellum, Female, P7, WT, replicate 1 Cerebellum, Female, P7,…
- GSM9204070 Cerebellum, Female, P7, KO, replicate 3 Cerebellum, Female, P7,…
- GSM9204071 Cerebellum, Male, P7, KO, replicate 1 Cerebellum, Male, P7, K…
- GSM9204072 Cerebellum, Male, P7, KO, replicate 2 Cerebellum, Male, P7, K…
- GSM9204073 Cerebellum, Male, P15, KO, replicate 1 Cerebellum, Male, P15, …
- GSM9204074 Cerebellum, Female, P15, WT, replicate 1 Cerebellum, Female, P15…
- GSM9204075 Cerebellum, Female, P15, KO, replicate 1 Cerebellum, Female, P15…
- GSM9204076 Cerebellum, Male, P15, WT, replicate 1 Cerebellum, Male, P15, …
- GSM9204077 Cerebellum, Female, P15, WT, replicate 2 Cerebellum, Female, P15…
- GSM9204078 Cerebellum, Male, P15, KO, replicate 2 Cerebellum, Male, P15, …
- GSM9204079 Cerebellum, Female, P15, KO, replicate 2 Cerebellum, Female, P15…
- GSM9204080 Cerebellum, Male, P15, KO, replicate 3 Cerebellum, Male, P15, …
- GSM9204081 Cerebellum, Male, P15, WT, replicate 2 Cerebellum, Male, P15, …
- GSM9204082 Cerebellum, Female, P30, KO, replicate 1 Cerebellum, Female, P30…
- GSM9204083 Cerebellum, Male, P30, KO, replicate 1 Cerebellum, Male, P30, …
- GSM9204084 Cerebellum, Female, P30, KO, replicate 2 Cerebellum, Female, P30…
- GSM9204085 Cerebellum, Female, P30, WT, replicate 1 Cerebellum, Female, P30…
- GSM9204086 Cerebellum, Female, P30, WT, replicate 2 Cerebellum, Female, P30…
- GSM9204087 Cerebellum, Female, P30, KO, replicate 3 Cerebellum, Female, P30…
- GSM9204088 Cerebellum, Male, P30, WT, replicate 1 Cerebellum, Male, P30, …
- GSM9204089 Cerebellum, Male, P30, KO, replicate 2 Cerebellum, Male, P30, …
- GSM9204090 Cerebellum, Male, P7, WT, replicate 2 Cerebellum, Male, P7, W…
- GSM9204091 Cerebellum, Female, P7, WT, replicate 2 Cerebellum, Female, P7,…
- GSM9204092 Cerebellum, Male, P30, KO, replicate 3 Cerebellum, Male, P30, …
- GSM9204093 Cerebellum, Female, P15, WT, replicate 3 Cerebellum, Female, P15…
- GSM9204094 Cerebellum, Male, P7, WT, replicate 3 Cerebellum, Male, P7, W…
- GSM9204095 Cerebellum, Female, P7, WT, replicate 3 Cerebellum, Female, P7,…
- GSM9204096 Cerebellum, Male, P7, WT, replicate 4 Cerebellum, Male, P7, W…
- GSM9204097 Cerebellum, Female, P7, KO, replicate 4 Cerebellum, Female, P7,…
- GSM9204098 Cerebellum, Female, P7, WT, replicate 4 Cerebellum, Female, P7,…
- GSM9204099 Cerebellum, Male, P7, KO, replicate 3 Cerebellum, Male, P7, K…
- GSM9204100 Cerebellum, Female, P30, WT, replicate 3 Cerebellum, Female, P30…
- GSM9204101 Cerebellum, Female, P30, WT, replicate 4 Cerebellum, Female, P30…
- GSM9204102 Cerebellum, Female, P30, KO, replicate 4 Cerebellum, Female, P30…
- GSM9204103 Cerebellum, Male, P15, KO, replicate 4 Cerebellum, Male, P15, …
- GSM9204104 Cerebellum, Male, P15, WT, replicate 3 Cerebellum, Male, P15, …
- GSM9204105 Cerebellum, Female, P15, WT, replicate 4 Cerebellum, Female, P15…
+ 135 more — browse all 175 samples with per-sample file links →
- GSE307546 Transcriptomics Analysis of bulk RNA from dissected brain regions (medial prefrontal cortex, cerebellum, and hippocampus) from 129/Sv-Cyp2e1tm1Gonz/J (CYP2E1-KO) and 129S1/SvImJ (WT) mice 48 samples shares hippocampus, cerebellum
- GSE278025 Maternal Micronutrient Insufficiency Exacerbates Growth Restriction with Ambient Heat on Placental and Fetal Development during Pregnancy 24 samples shares insufficiency, placental
- GSE319614 Bulk RNA-seq transcriptome profiling of hippocampus across 17 autism spectrum disorder mouse models 269 samples shares hippocampus
- GSE284500 Transcriptional profiling of hippocampus from a zQ175 KI mouse model of Huntington's disease treated with either HTT-10150 siRNA targeting full-length HTT or combination of HTT-634 and HTT-486 siRNAs targeting HTT1a 192 samples shares hippocampus
- GSE292224 Distinct molecular mechanisms of stress habituation in the mouse hippocampus [bulk RNA-seq] 190 samples shares hippocampus
- GSE299937 Srrm2 haploinsufficiency drives SynGAP-γ reduction, Agap3 mis-splicing, and oligodendrocyte deficits in a genetic mouse model of schizophrenia 180 samples shares insufficiency
- GSE271598 Transcriptional Dysregulation in the Hippocampus of a Mouse Model for Parkinson's - Linked Cognitive Decline is Driven by Sex, Age, and Alpha-synuclein overexpression 64 samples shares hippocampus
- GSE278035 RNA-Seq of hippocampus in founder mice 64 samples shares hippocampus
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.