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The effect of Anaerostipes caccaei and Bifidobacterium bifidum on epithelial cells of colon

GSE306638 Mus musculus Expression profiling by high throughput sequencing 9 samples Submitted 2025/09/03 Platform GPL34328
Summary
The purpose of this study is to determine whether cross feeding relationships can contribute to the alleviation of colitis. The two strains used in this study are Anaerostipes caccae and Bifidobacterium bifidum. Both strains are clearly present in significant amounts in the intestines of healthy humans. A. caccae is a butyrate-producing bacterium that uses lactic acid and acetate to produce butyrate. On the other hand, B. bifidum is known to produce lactic acid and acetate. The purpose of this study is to confirm the effect of the ecological network between the two strains on the improvement of colitis, particularly in terms of protecting intestinal epithelial cells.
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Also filed as BioProject PRJNA1311548 and SRA study SRP613735. Searching any of these in the dataset finder brings you back here.

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