SPP1+ Macrophages Contribute to Hair Growth in Contact Hypersensitivity
RNA-seq (gene expression) · mouse · 21 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 21 samples: 6 conditions, mostly in triplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE306678_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1311613 and SRA study SRP613037. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 18 samples.
How we read this: 6 replicated groups read from 21 sample titles; they account for 18 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9194282 DPCP Visium HD D0-D3
- GSM9202382 Control EpSCs-1 Control EpSCs
- GSM9202383 Control EpSCs-2 Control EpSCs
- GSM9202384 Control EpSCs-3 Control EpSCs
- GSM9202385 Control Germ-1 Control Germ
- GSM9202386 Control Germ-2 Control Germ
- GSM9202387 Control Germ-3 Control Germ
- GSM9202388 Control Bulge-1 Control Bulge
- GSM9202389 Control Bulge-2 Control Bulge
- GSM9202390 Control Bulge-3 Control Bulge
- GSM9202391 DPCP EpSCs-1 DPCP EpSCs
- GSM9202392 DPCP EpSCs-2 DPCP EpSCs
- GSM9202393 DPCP EpSCs-3 DPCP EpSCs
- GSM9202394 DPCP Germ-1 DPCP Germ
- GSM9202395 DPCP Germ-2 DPCP Germ
- GSM9202396 DPCP Germ-3 DPCP Germ
- GSM9202397 DPCP Bulge-1 DPCP Bulge
- GSM9202398 DPCP Bulge-2 DPCP Bulge
- GSM9202399 DPCP Bulge-3 DPCP Bulge
- GSM9202400 CD45 DPCP day2, Control day0
- GSM9202401 DPCP day2 vs Control day0
- GSE273148 TGF-β builds a dual immune barrier in colorectal cancer by impairing T cell recruitment and instructing immunosuppressive SPP1+ macrophages 23 samples shares spp1, macrophages
- GSE263545 Resident and recruited macrophages differentially contribute to cardiac healing after myocardial ischemia [scRNA-seq] 10 samples shares macrophages, contribute
- GSE280003 Gpnmb and Spp1 mark a conserved macrophage injury response masking fibrosis-specific programming in the lung 81 samples shares spp1
- GSE302019 Bulk RNA sequencing to investigate transcriptional profiles of lung macrophage subpopulations isolated from wild-type C57BL/6J and Spp1-EGFP knock-in reporter mice subjected to intratracheal administration of bleomycin or PBS. 24 samples shares spp1
- GSE300922 Xin-Zi-Sheng-Wan Decoction Alleviates Hyperuricemia-Induced Renal Injury by Modulating SPP1-CD44-Mediated Macrophage Infiltration and SRC/FAK/β-Catenin Signaling Pathway 12 samples shares spp1
- GSE290434 A stress response axis in tumor-associated macrophages dictates phenotype heterogeneity and immunotherapy evasion 21 samples shares macrophages
- GSE301899 mTOR signaling contributes to system-driven rhythmic gene expression in mouse liver 282 samples shares contribute
- GSE272755 Transcriptional effects of lysosome stress on mouse bone marrow-derived macrophages and primary microglia 263 samples shares macrophages
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.