GEO series
Bulk RNA-seq analysis of PDAC PANC-1 cells silenced with siRNA targeting myoferlin or treated with WJ460.
GSE306771
Homo sapiens
Expression profiling by high throughput sequencing
12 samples
2025/08/28
GPL24676
Summary
Myoferlin is a transmembrane protein, encoded by the MYOF gene, initially identified in myoblasts for its crucial role in membrane biology via its C2 domain. MYOF was overexpressed in PDAC and functional studies have revealed myoferlin's critical involvement in mitochondrial adaptation, metatstasis and ferroptosis.
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Paper (PMID 41062852) ↗
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