GEO series
Transcriptomic profiling of THP-1 and RPMI-8226 cells stimulated with innate immune agonists
GSE308610
Homo sapiens
Expression profiling by high throughput sequencing
26 samples
2025/10/10
GPL34284
Summary
This study aimed to investigate the transcriptional responses of human THP-1 monocytes and RPMI-8226 multiple myeloma cells to various innate immune agonists. Cells were treated with ALPK1 agonist (ADP-Hep or UDSP-Hep), TLR7/8 agonist (R848), or STING agonist (ADU-S100) at different concentrations for 4 hours, and RNA-seq was performed to characterise the downstream gene expression programmes triggered by these stimuli.
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